金黄色葡萄球菌噬菌体 vBSM-A1 的全基因组分析。
Complete genome analysis of a Staphylococcus aureus phage (vBSM-A1).
机构信息
School of Bioengineering, Dalian University of Technology, Dalian, 116024, People's Republic of China.
Aimei Hissen Vaccine (Dalian) Co., Ltd., Dalian, People's Republic of China.
出版信息
Arch Microbiol. 2020 Sep;202(7):1617-1626. doi: 10.1007/s00203-020-01867-2. Epub 2020 Apr 6.
In this study, the genome of a new strain of lytic Staphylococcus aureus Herelleviridae, vBSM-A1, was characterized and annotated. The phage was isolated from sewage samples collected in Xinjiang Province, China. The genome of vBSM-A1 was found to comprise a linear double-stranded DNA of 140,654 bp length, with a G + C content of 30.33%. A total of 215 ORFs were detected in the phage DNA, 74 of which were functionally assigned. The 3D structure model of endolysin LysK (ORF 143) was created using Phyre2.
在这项研究中，我们对一株新型溶葡萄球菌噬菌体（Herelleviridae 科）vBSM-A1 的基因组进行了特征描述和注释。该噬菌体是从中国新疆的污水样本中分离得到的。vBSM-A1 的基因组是一条长度为 140654bp 的线性双链 DNA，GC 含量为 30.33%。在噬菌体 DNA 中检测到了 215 个开放阅读框，其中 74 个具有功能注释。使用 Phyre2 构建了内切溶菌酶 LysK（ORF143）的 3D 结构模型。
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