Xinxiang Key Laboratory of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, 453003 Henan, PR China.
Xinxiang Key Laboratory of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, 453003 Henan, PR China - MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095 Jiangsu, PR China.
Parasite. 2020;27:23. doi: 10.1051/parasite/2020018. Epub 2020 Apr 7.
Toxoplasma gondii is an obligate intracellular protozoan parasite with global distribution. However, data on T. gondii infection among children in primary school in Henan province, central China were lacking. In this study, 2451 serum samples of primary school children in this province were collected from September 2015 to October 2018 and evaluated for T. gondii antibodies using an enzyme-linked immunosorbent assay (ELISA). The overall seroprevalence was 9.51% (233/2451), of which 7.59% (186/2451) showed IgG positivity, 0.73% (18/2451) IgM and 1.18% (29/2451) both. The main risk factors related to T. gondii infections were the age of children, residence area, contact with cats, and exposure to soil. Moreover, hand washing before eating was considered a protective factor. Seroprevalence of T. gondii infection among the study population was common, emphasizing the need to prevent and control this infection. This is the first report of T. gondii seroprevalence in primary school children in Henan province, central China.
刚地弓形虫是一种全球性分布的专性细胞内寄生原虫。然而，目前关于中国中部河南省小学生弓形虫感染的数据尚缺乏。在本研究中，于 2015 年 9 月至 2018 年 10 月间，采集了该省 2451 名小学生的血清样本，采用酶联免疫吸附试验（ELISA）检测弓形虫抗体。总血清阳性率为 9.51%（233/2451），其中 IgG 阳性率为 7.59%（186/2451），IgM 阳性率为 0.73%（18/2451），两者均阳性率为 1.18%（29/2451）。与弓形虫感染相关的主要危险因素为儿童年龄、居住地区、与猫的接触和接触土壤。此外，饭前洗手被认为是一种保护因素。研究人群中弓形虫感染的血清阳性率较高，强调需要预防和控制这种感染。这是中国中部河南省小学生弓形虫血清阳性率的首次报告。
