Wu Jiangjiexing, Li Sirong, Wei Hui
Department of Biomedical Engineering, College of Engineering and Applied Sciences, Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing 210093, China.
Nanoscale Horiz. 2018 Jul 1;3(4):367-382. doi: 10.1039/c8nh00070k. Epub 2018 May 31.
Over decades, as alternatives to natural enzymes, highly-stable and low-cost artificial enzymes have been widely explored for various applications. In the field of artificial enzymes, functional nanomaterials with enzyme-like characteristics, termed as nanozymes, are currently attracting immense attention. Significant progress has been made in nanozyme research due to the exquisite control and impressive development of nanomaterials. Since nanozymes are endowed with unique properties from nanomaterials, an interesting investigation is multifunctionality, which opens up new potential applications for biomedical sensing and sustainable chemistry due to the combination of two or more distinct functions of high-performance nanozymes. To highlight the progress, in this review, we discuss two representative types of multifunctional nanozymes, including iron oxide nanomaterials with magnetic properties and metal nanomaterials with surface plasmon resonance. The applications are also covered to show the great promise of such multifunctional nanozymes. Future challenges and prospects are discussed at the end of this review.
几十年来，作为天然酶的替代品，高稳定性和低成本的人工酶已被广泛探索用于各种应用。在人工酶领域，具有类酶特性的功能性纳米材料，即纳米酶，目前正引起极大关注。由于纳米材料的精确控制和显著发展，纳米酶研究取得了重大进展。由于纳米酶具有纳米材料赋予的独特性质，一个有趣的研究方向是多功能性，由于高性能纳米酶的两种或更多种不同功能的结合，这为生物医学传感和可持续化学开辟了新的潜在应用。为突出这一进展，在本综述中，我们讨论了两种代表性的多功能纳米酶，包括具有磁性的氧化铁纳米材料和具有表面等离子体共振的金属纳米材料。还涵盖了其应用以展示此类多功能纳米酶的巨大前景。本综述结尾讨论了未来的挑战和前景。
