State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, 361102, China.
Nanoscale Horiz. 2019 Jan 1;4(1):190-195. doi: 10.1039/c8nh00276b. Epub 2018 Oct 15.
A multi-level supramolecular system produced by single-step Fe-mediated ionic crosslinking self-assembly can overcome the critical issues of current sonodynamic therapy (SDT) and address the need to monitor therapeutic effects in vivo with a non-invasive approach. This rational design of organic sonosensitizer-based formulation shows great potential for clinical SDT against deep-seated cancer.
一步法 Fe 介导的离子交联自组装制备的多级超分子体系可以克服当前声动力学疗法（SDT）的关键问题，并满足用非侵入性方法在体内监测治疗效果的需求。这种基于有机声敏剂的配方的合理设计为临床深部癌症的 SDT 治疗提供了巨大的潜力。
