聚多巴胺包覆的磁性介孔硅纳米粒子用于多模式癌症诊疗一体化。
Polydopamine-coated magnetic mesoporous silica nanoparticles for multimodal cancer theranostics.
机构信息
The Key Laboratory of Resource Chemistry of Ministry of Education, Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, Shanghai Normal University, Shanghai 200234, People's Republic of China.
出版信息
J Mater Chem B. 2019 Jan 21;7(3):368-372. doi: 10.1039/c8tb03021a. Epub 2018 Dec 19.
Polydopamine-coated magnetic mesoporous silica nanoparticles have been designed by loading ultrasmall iron oxide nanoparticles within hollow mesoporous silica nanopartricles and then coating polydopamine onto the particle surface. The developed nanoplatform displayed improved colloidal stability, enhanced r relaxivity and near infrared absorption feature, affording their use for multimodal cancer theranostics.
聚多巴胺包覆的磁性介孔硅纳米粒子是通过将超小的氧化铁纳米粒子负载在中空介孔硅纳米粒子中，然后在颗粒表面包覆聚多巴胺而设计的。所开发的纳米平台显示出改善的胶体稳定性、增强的 r 弛豫率和近红外吸收特性，可用于多模式癌症治疗。
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