Chen Shuai, Li Qiaoying, Wang Xin, Yang Ying-Wei, Gao Hui
School of Chemistry and Chemical Engineering, Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, Tianjin University of Technology, Tianjin 300384, P. R. China.
J Mater Chem B. 2018 Aug 28;6(32):5198-5214. doi: 10.1039/c8tb01519h. Epub 2018 Jul 31.
Bacterial infections have severely affected human health, leading to a considerable number of human deaths. Inevitably direct and indirect contacts with medical devices, food packing and daily supplies with harmful bacteria are among the major transmission routes of bacterial infections. Effective bacterial theranostic systems that combine diagnostic functions and therapeutic effects have received extensive attention due to their excellent features including high efficiency, real-time performance and low drug resistance. In this review article, we summarize the recent advances of antibacterial materials including natural antibacterial compounds, quaternary ammonium polymers, and inorganic or hybrid nanoparticles with the dual functions of detection and imaging. In particular, multiple imaging modalities and antibacterial modalities are systematically discussed in order to provide a better understanding of modern theranostics.
细菌感染严重影响人类健康，导致大量人员死亡。不可避免地，与带有有害细菌的医疗设备、食品包装和日常用品的直接和间接接触是细菌感染的主要传播途径之一。结合诊断功能和治疗效果的有效细菌诊疗系统因其高效、实时和低耐药性等优异特性而受到广泛关注。在这篇综述文章中，我们总结了抗菌材料的最新进展，包括天然抗菌化合物、季铵聚合物以及具有检测和成像双重功能的无机或杂化纳米颗粒。特别地，系统地讨论了多种成像模式和抗菌模式，以便更好地理解现代诊疗学。
