角膜膨隆症患者的血清炎症生物标志物。
Serum Inflammation Biomarkers in Patients with Keratoconus.
机构信息
Faculty of Medicine, Department of Ophthalmology, Kafkas University, Kafkas, Turkey.
Faculty of Medicine, Department of Ophthalmology, Erzincan University, Erzincan, Turkey.
出版信息
Ocul Immunol Inflamm. 2021 Aug 18;29(6):1164-1167. doi: 10.1080/09273948.2020.1741648. Epub 2020 Apr 7.
: To evaluate inflammation-sensitive parameters, namely the neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), eosinophil count, erythrocyte distribution width (RDW), and CRP/albumin ratio in patients with keratoconus (KC).: Thirty-five patients with KC and 30 healthy people (control group) were included in the study. Complete blood count measurements were performed in all subjects, and NLR, PLR and the CRP/albumin ratio were calculated.: NLR was determined as 2.01 ± 0.53 in patients with KC and 1.97 ± 0.41 in the control group. PLR was 146.20 ± 23.32 in the KC group and 121.45 ± 31.75 in the healthy group. The CRP/albumin ratio was determined as 0.33 ± 0.09 in the KC group and 0.29 ± 0.11 in the healthy group.: Although no significant difference was found between the groups in terms of NLR, CRP/albumin ratio and RDW levels, PLR was significantly higher in the KC group.
目的
评估炎症敏感参数，即中性粒细胞/淋巴细胞比值（NLR）、血小板/淋巴细胞比值（PLR）、嗜酸性粒细胞计数、红细胞分布宽度（RDW）和 C 反应蛋白/白蛋白比值在圆锥角膜（KC）患者中的变化。
方法
本研究纳入了 35 例 KC 患者和 30 名健康人（对照组）。所有受试者均进行了全血细胞计数测量，并计算 NLR、PLR 和 CRP/白蛋白比值。
结果
KC 组的 NLR 为 2.01±0.53，对照组为 1.97±0.41。KC 组的 PLR 为 146.20±23.32，健康组为 121.45±31.75。KC 组的 CRP/白蛋白比值为 0.33±0.09，健康组为 0.29±0.11。
结论
尽管 NLR、CRP/白蛋白比值和 RDW 水平在两组间无显著差异，但 KC 组的 PLR 明显更高。
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