Al-Zalabani Abdulmohsen H
Department of Family and Community Medicine, College of Medicine, Taibah University, Al-Madinah, Saudi Arabia.
Tob Induc Dis. 2020 Mar 19;18:18. doi: 10.18332/tid/118722. eCollection 2020.
The Gulf Cooperation Council (GCC) member countries include Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and United Arab Emirates. The current study aims to provide an estimate of the population fractions of cancer cases attributable to tobacco smoking in the GCC countries.
Population attributable fraction (PAF) was calculated for cancers that were listed by the International Agency for Research on Cancer (IARC) to have sufficient evidence of causal association. The estimated number of incident cancer cases in GCC countries were retrieved from the IARC GLOBOCAN database. The prevalence estimates of current tobacco smoking among persons aged ≥15 years were obtained from the World Health Organization report on prevalence of tobacco smoking. Relative risk estimates for various cancers were obtained from published meta-analyses. Summary PAFs and cancer cases attributable to tobacco smoking are reported by country, sex, and cancer type.
Tobacco smoking was responsible for 2536 (16.3%) of cancer cases in GCC countries in 2018. It accounted for 22.8% (n=2396) and 2.8% (n=140) of cancer cases among males and females, respectively. Among males, the highest number of cancer incident cases attributable to smoking was lung cancer (807) followed by urinary bladder (328), and colorectal cancer (305). Among females, the highest number of cancer cases attributable to smoking was lung cancer (62) followed by lip and oral cavity (13), and cervical cancer (13).
Tobacco smoking accounted for a large portion of cancer cases attributable to preventable risk factors in GCC countries. Preventive efforts focusing on reducing tobacco smoking should be a high priority in GCC countries.
海湾合作委员会（GCC）成员国包括巴林、科威特、阿曼、卡塔尔、沙特阿拉伯和阿拉伯联合酋长国。本研究旨在估算海湾合作委员会国家中可归因于吸烟的癌症病例的人口比例。
对国际癌症研究机构（IARC）列出的有充分因果关联证据的癌症计算人群归因分数（PAF）。从IARC全球癌症负担数据库中检索海湾合作委员会国家的估计新发癌症病例数。15岁及以上人群当前吸烟率的估计值来自世界卫生组织关于吸烟率的报告。各种癌症的相对风险估计值来自已发表的荟萃分析。按国家、性别和癌症类型报告汇总的PAF和归因于吸烟的癌症病例。
2018年，吸烟导致海湾合作委员会国家2536例（16.3%）癌症病例。其中男性癌症病例中吸烟所致占22.8%（n = 2396），女性占2.8%（n = 140）。在男性中，归因于吸烟的癌症新发病例数最多的是肺癌（807例），其次是膀胱癌（328例）和结直肠癌（305例）。在女性中，归因于吸烟的癌症病例数最多的是肺癌（62例），其次是唇和口腔癌（13例）和宫颈癌（13例）。
在海湾合作委员会国家，吸烟占可预防风险因素导致的癌症病例的很大一部分。在海湾合作委员会国家，将重点放在减少吸烟上的预防措施应成为高度优先事项。
