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Editorial: C1q: A Molecular Bridge to Innate and Adaptive Immunity.

作者信息

Kishore Uday, Ghebrehiwet Berhane

机构信息

Biosciences, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom.

Department of Medicine, State University of New York, New York, NY, United States.

出版信息

Front Immunol. 2020 Mar 17;11:417. doi: 10.3389/fimmu.2020.00417. eCollection 2020.

DOI:10.3389/fimmu.2020.00417
PMID:32256491
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7090096/
Abstract
摘要

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本文引用的文献

1
Nasal allergen-neutralizing IgG antibodies block IgE-mediated responses: Novel biomarker of subcutaneous grass pollen immunotherapy.鼻过敏原中和 IgG 抗体可阻断 IgE 介导的反应：皮下草花粉免疫治疗的新型生物标志物。
J Allergy Clin Immunol. 2019 Mar;143(3):1067-1076. doi: 10.1016/j.jaci.2018.09.039. Epub 2018 Nov 14.
2
C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation.C1q在肿瘤微环境中作为一种促癌因子发挥作用，与补体激活无关。
Nat Commun. 2016 Feb 1;7:10346. doi: 10.1038/ncomms10346.
3
C1q protein binds to the apoptotic nucleolus and causes C1 protease degradation of nucleolar proteins.C1q蛋白与凋亡的核仁结合，并导致核仁蛋白的C1蛋白酶降解。
J Biol Chem. 2015 Sep 11;290(37):22570-80. doi: 10.1074/jbc.M115.670661. Epub 2015 Jul 31.
4
Emerging and Novel Functions of Complement Protein C1q.补体蛋白C1q的新出现及新颖功能
Front Immunol. 2015 Jun 29;6:317. doi: 10.3389/fimmu.2015.00317. eCollection 2015.
5
Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes.补体 C1q 激活经典 Wnt 信号通路并促进与衰老相关的表型。
Cell. 2012 Jun 8;149(6):1298-313. doi: 10.1016/j.cell.2012.03.047.
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The human c1q globular domain: structure and recognition of non-immune self ligands.人 C1q 球形结构域：非免疫源性自身配体的结构与识别。
Front Immunol. 2012 Jan 6;2:92. doi: 10.3389/fimmu.2011.00092. eCollection 2011.
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Complement and non-complement activating functions of C1q: a prototypical innate immune molecule.C1q 的补体和非补体激活功能：一种典型的先天免疫分子。
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