Raina Rupesh, Nair Nikhil, Chakraborty Ronith, Nemer Lena, Dasgupta Rahul, Varian Kenneth
Department of Nephrology, Akron Nephrology Associates at Cleveland Clinic Akron General Medical Center, Akron, OH, USA.
Department of Pediatric Nephrology, Akron Children's Hospital, Akron, OH, USA.
Cardiol Res. 2020 Apr;11(2):76-88. doi: 10.14740/cr955. Epub 2020 Mar 10.
Cardiorenal syndrome (CRS) encompasses various disorders of the heart and kidneys; dysfunction of one organ leads to acute or chronic dysfunction of the other. It incorporates the intersection of heart-kidney interactions across several mediums, hemodynamically, through the alterations in neurohormonal markers, and increased venous and renal pressure, all of which are hallmarks of its clinical phenotypes. This article explores the epidemiology, pathology, classification and treatment of each type of CRS.
心肾综合征(CRS)涵盖了心脏和肾脏的多种病症;一个器官的功能障碍会导致另一个器官的急性或慢性功能障碍。它包含了心肾相互作用在多个层面的交集,包括血流动力学层面,通过神经激素标志物的改变以及静脉压和肾内压的升高,所有这些都是其临床表型的特征。本文探讨了每种类型CRS的流行病学、病理学、分类和治疗方法。