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童年不良经历对学龄青少年抑郁症状、患病率及严重程度的影响

The Role of Adverse Childhood Experience on Depression Symptom, Prevalence, and Severity among School Going Adolescents.

作者信息

Tsehay Mekonnen, Necho Mogesie, Mekonnen Werkua

机构信息

Department of Psychiatry, College of Medicine and Health Science, Wollo University, Wollo, Ethiopia.

Department of Psychiatry, College of Health Science, Mekelle University, Mekelle, Ethiopia.

出版信息

Depress Res Treat. 2020 Mar 18;2020:5951792. doi: 10.1155/2020/5951792. eCollection 2020.

Abstract

METHODS

A cross-sectional school-based study was employed. Five hundred forty-six secondary school students were selected using multistage sampling technique from 5 selected secondary schools. We obtained retrospective information on adverse childhood experiences of adolescents by ACEs, self-reported 10-item questionnaire, and current depression prevalence and severity by PHQ-9. Multivariate linear regression models were used to estimate child depression severity by retrospective ACE count.

RESULTS

Among the 546 adolescents who participated in this study, 285 (50.7%) of the participants answered yes to at least one or more questions among the total 10 questions of ACEs. Experiences of ACEs increased the risk for depressive symptoms, with unstandardized  = 1.123 ( = 1.123, 95% CI (0.872, 1.373). We found a strong, dose-response relationship between the ACE score and the probability of lifetime and recent depressive disorders ( < 0.0001).

CONCLUSIONS

The number of ACEs has a graded relationship to both the prevalence and severity of depressive symptoms. These results suggest that exposure to ACEs is associated with an increased risk of depressive symptoms up to decades after their occurrence. Early recognition of childhood abuse and appropriate intervention may thus play an important role in the prevention of depressive disorders throughout the life span.

摘要

方法

采用基于学校的横断面研究。通过多阶段抽样技术从5所选定的中学选取了546名中学生。我们通过儿童期不良经历问卷(ACEs)获取青少年童年不良经历的回顾性信息,通过患者健康问卷-9(PHQ-9)进行自我报告的10项问卷调查以了解当前抑郁症的患病率和严重程度。使用多元线性回归模型通过回顾性ACE计数来估计儿童抑郁症的严重程度。

结果

在参与本研究的546名青少年中,285名(50.7%)参与者在ACEs全部10个问题中至少对一个或多个问题回答“是”。ACEs经历增加了抑郁症状的风险,非标准化β = 1.123(β = 1.123,95%置信区间(0.872,1.373))。我们发现ACE得分与终生及近期抑郁障碍的概率之间存在强剂量反应关系(P < 0.0001)。

结论

ACEs的数量与抑郁症状的患病率和严重程度均呈分级关系。这些结果表明,接触ACEs与出现后数十年内抑郁症状风险增加有关。因此,早期识别儿童期虐待并进行适当干预可能在预防终生抑郁障碍中发挥重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1baa/7104267/8543c5fbd5e4/DRT2020-5951792.001.jpg

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