Lim Adeline Yi Ling, Mattke Adrian Christian, Clark Julia Elizabeth, Pinzon-Charry Alberto, Alphonso Nelson, Kapur Nitin
Department of Respiratory and Sleep Medicine, Queensland Children's Hospital, 501 Stanley Street, South Brisbane, Queensland 4101, Australia.
Department of Pediatric Intensive Care, Queensland Children's Hospital, 501 Stanley Street, South Brisbane, Queensland 4101, Australia.
Case Rep Pediatr. 2020 Mar 15;2020:5740304. doi: 10.1155/2020/5740304. eCollection 2020.
is recognized as an opportunistic pathogen in immunosuppressed patients. We report a case of severe pneumonia (PCP) in an infant with acquired combined immunodeficiency secondary to maternal chemotherapy exposure during the second and third trimesters of pregnancy. The infant required cardiorespiratory support with veno-venous extracorporeal membrane oxygenation (VV-ECMO) for severe respiratory failure. This case highlights the potential for severe acquired immunodeficiency in this patient cohort and further postnatal surveillance is highly recommended.
在免疫抑制患者中被认为是一种机会性病原体。我们报告了一例婴儿严重肺炎（肺孢子菌肺炎）病例，该婴儿因母亲在妊娠中期和晚期接受化疗而获得性联合免疫缺陷。该婴儿因严重呼吸衰竭需要静脉 - 静脉体外膜肺氧合（VV - ECMO）进行心肺支持。该病例突出了这一患者群体中严重获得性免疫缺陷的可能性，强烈建议进一步进行产后监测。
