Sert Ekrem T, Akilli Nazire, Köylü Ramazan, Cander Basar, Kokulu Kamil, Köylü Öznur
Emergency Medicine, Aksaray University Medical School, Aksaray, TUR.
Emergency Medicine, Konya Training and Research Hospital, University of Health Sciences, Konya, TUR.
Cureus. 2020 Feb 28;12(2):e7135. doi: 10.7759/cureus.7135.
Objective The purpose of this study was to determine the effect of beta-trace protein (BTP) levels at the time of admission and at 8th hour on diagnosis and prognosis in patients who were under treatment and follow-up with acute coronary syndrome (ACS) diagnosis at coronary intensive care unit and emergency department. Materials and Methods This study was conducted between June 2014 and December 2014 at the Emergency Department of Konya Training and Research Hospital. Demographic characteristics, background, vital findings, laboratory findings, blood BTP levels, coronary angiography results, and echocardiography findings of the patients diagnosed with ACS were recorded. Risk classification was performed for patients with ACS and their mortality rates were recorded. Relation of BTP level with risk classification and mortality was evaluated. Results A total of 174 individuals, 138 patients and 36 control subjects, were included in the study. No significant difference was detected between BTP levels at the time of admission and at 8 hour in the patient group (p=0.883). There was no difference between the patient and control groups in terms of the BTP level (p=0.335). Ten patients (7.2%) died in the patient group. BTP levels measured at the time of admission and at 8th hour were not different for dead and living patients (admission p=0.085, 8 hour p=0.141). Conclusion We determined that there was a lack of biochemical markers that could be used for the prognosis of serum BTP levels in patients admitting to the emergency unit with ACS.
目的 本研究旨在确定入院时及8小时时β-微量蛋白(BTP)水平对在冠心病重症监护病房和急诊科接受急性冠状动脉综合征(ACS)诊断治疗及随访患者的诊断和预后的影响。
材料与方法 本研究于2014年6月至2014年12月在科尼亚培训与研究医院急诊科进行。记录诊断为ACS患者的人口统计学特征、背景、生命体征、实验室检查结果、血液BTP水平、冠状动脉造影结果及超声心动图检查结果。对ACS患者进行风险分类并记录其死亡率。评估BTP水平与风险分类及死亡率的关系。
结果 本研究共纳入174例个体,其中138例患者和36例对照者。患者组入院时和8小时时的BTP水平无显著差异(p = 0.883)。患者组与对照组的BTP水平无差异(p = 0.335)。患者组中有10例(7.2%)死亡。死亡和存活患者入院时及8小时时测得的BTP水平无差异(入院时p = 0.085,8小时时p = 0.141)。
结论 我们确定,对于因ACS入住急诊科的患者,缺乏可用于血清BTP水平预后判断的生化标志物。