Smulski Sebastian, Turlewicz-Podbielska Hanna, Wylandowska Agata, Włodarek Jan
Department of Internal Diseases and Diagnosis, Poznań, Poland.
Department of Preclinical Sciences and Infectious Diseases, Faculty of Veterinary Medicine and Animal Sciences, Poznań University of Life Sciences, 60-637 Poznań, Poland.
J Vet Res. 2020 Jan 20;64(1):119-126. doi: 10.2478/jvetres-2020-0002. eCollection 2020 Mar.
Due to increasing bacterial antibiotic resistance and the consumers' tendency to choose organic products, cattle farmers are interested in alternative methods of calf diarrhoea treatment. This is a major challenge for veterinarians. Few methods of non-antibiotic treatment that bring satisfactory results have been reported in the related literature so far. In this article, the authors compare different non-antibiotic methods of diarrhoea prevention and treatment in calves. Among the alternatives discussed are herbs, probiotics, prebiotics and synbiotics, lactoferrin, and bacteriophages. It was found that the best results could be achieved through the use of pro-, pre- and synbiotics. However, the authors would like to point out that with the expansion of knowledge about the practical use of broad-scale bacteriophages, they could be the best alternative to antibiotics.
由于细菌对抗生素的耐药性不断增加以及消费者倾向于选择有机产品，养牛户对犊牛腹泻的替代治疗方法很感兴趣。这对兽医来说是一项重大挑战。到目前为止，相关文献中报道的能带来满意效果的非抗生素治疗方法很少。在本文中，作者比较了犊牛腹泻预防和治疗的不同非抗生素方法。讨论的替代方法包括草药、益生菌、益生元、合生元、乳铁蛋白和噬菌体。研究发现，通过使用益生菌、益生元和合生元可以取得最佳效果。然而，作者想指出的是，随着对大规模噬菌体实际应用知识的扩展，它们可能成为抗生素的最佳替代品。
