Gultekin Fatih, Oner Manolya Eser, Savas Hasan Basri, Dogan Bora
Department of Medical Biochemistry, Saglik Bilimleri University Faculty of Medicine, Istanbul, Turkey.
Department of Food Engineering, Alanya Alaaddin Keykubat University Faculty of Engineering, Antalya, Turkey.
North Clin Istanb. 2019 Jul 17;7(2):192-200. doi: 10.14744/nci.2019.92499. eCollection 2020.
The use of food additives in food production is inevitable in this modern world. Although only a safe amount of food additives is approved, their safety has always been questioned. To our knowledge, the effects of food additives on microbiota have not been investigated in a detailed manner in the literature so far. In this review, the effects of artificial sweeteners, sugar alcohols, emulsifiers, food colorants, flavor enhancers, thickeners, anticaking agents, and preservatives on microbiota were reviewed. Even though most of the results illustrated negative outcomes, few of them showed positive effects of food additives on the microbiota. Although it is difficult to obtain exact results due to differences in experimental animals and models, said the findings suggest that nonnutritive synthetic sweeteners may lead to glucose intolerance by affecting microbiota and a part of sugar alcohols show similar effects like probiotics.
在当今这个现代世界，食品生产中使用食品添加剂是不可避免的。尽管只有安全剂量的食品添加剂被批准使用，但其安全性一直受到质疑。据我们所知，迄今为止，文献中尚未对食品添加剂对微生物群的影响进行详细研究。在本综述中，我们回顾了人工甜味剂、糖醇、乳化剂、食用色素、增味剂、增稠剂、抗结剂和防腐剂对微生物群的影响。尽管大多数结果显示出负面结果，但也有少数结果表明食品添加剂对微生物群有积极影响。尽管由于实验动物和模型的差异难以获得确切结果，但上述研究结果表明，非营养性合成甜味剂可能通过影响微生物群导致葡萄糖不耐受，并且一部分糖醇显示出与益生菌类似的效果。
