Sugawara Akiyoshi, Asaoka Kenzo, Ding Shinn-Jyh
Sugawara Dental Clinic, Nihon University School of Dentistry, Tokyo, Japan.
J Mater Chem B. 2013 Feb 28;1(8):1081-1089. doi: 10.1039/c2tb00061j. Epub 2012 Dec 14.
Although autografts are considered to be the current gold standard, there is still clinical demand for synthetic bone graft substitutes. Calcium phosphate cements (CPCs) have many favourable properties that support their clinical use in the repair of bone defects. Although the translation of CPCs from the bench to the bedside has been quite successful, some issues remain. This review article provides an overview of the recent progress in the development of CPC-based materials and also emphasises the challenges facing clinical applications. The next generation of CPCs with unique properties is emerging for specific clinical applications.
尽管自体骨移植被认为是当前的金标准，但临床上对合成骨移植替代物仍有需求。磷酸钙骨水泥（CPCs）具有许多有利特性，支持其在骨缺损修复中的临床应用。尽管CPCs从实验室到临床的转化相当成功，但仍存在一些问题。这篇综述文章概述了基于CPCs材料开发的最新进展，并强调了临床应用面临的挑战。具有独特性能的新一代CPCs正在涌现，以用于特定的临床应用。
