Egorov A D, Alferova I V, Poliakova A P
Kosm Biol Aviakosm Med. 1988 Jul-Aug;22(4):19-26.
This paper presents data on the phasic structure of the cardiac cycle of the left ventricle of cosmonauts who flew for 96 to 237 days on Salyut-6-Soyuz and Salyut-7-Soyuz. Cardiodynamic changes at rest that developed largely during the first month of flight involved a mild preload syndrome. During flight months 2 to 8 the cardiac function became relatively stabilized. Provocative tests, i. e. LBNP and exercise tests, presented inflight modified the relationship between cardiac cycle phases when compared to the Earth observations. The modifications are suggestive of predominant adrenergic effects on the heart. Analysis of the phasic structure of the cardiac cycle has revealed no cardiovascular deconditioning. All the variations can be regarded as adaptive reactions to microgravity.
本文展示了在“礼炮6号-联盟号”和“礼炮7号-联盟号”上飞行96至237天的宇航员左心室心动周期的相位结构数据。飞行第一个月主要出现的静息状态下的心脏动力学变化包括轻度前负荷综合征。在飞行第2至8个月期间，心脏功能相对稳定。与在地球上的观测结果相比，飞行中进行的激发试验，即下体负压试验和运动试验，改变了心动周期各阶段之间的关系。这些改变表明肾上腺素能对心脏起主要作用。对心动周期相位结构的分析未发现心血管功能失调。所有这些变化都可被视为对微重力的适应性反应。
