Chen Nai-Tzu, Cheng Shih-Hsun, Souris Jeffrey S, Chen Chin-Tu, Mou Chung-Yuan, Lo Leu-Wei
Division of Medical Engineering Research, National Health Research Institutes, Zhunan, Taiwan, R. O. C..
J Mater Chem B. 2013 Jul 7;1(25):3128-3135. doi: 10.1039/c3tb20249f. Epub 2013 May 16.
Mesoporous silica nanoparticles (MSNs), with their intrinsically large and easily functionalized surface areas and pore volumes, are particularly well-suited to efficient conveyance of a wide variety of therapeutic agents. When combined with other organic/inorganic nanomaterials, the resultant organic/inorganic-MSN hybrids demonstrate unique synergies and even greater versatility. In this paper, we describe the current status and future prospects of MSNs and organic/inorganic-MSN hybrids for combined therapeutic and diagnostic - theranostic - biomedical applications.
介孔二氧化硅纳米颗粒（MSNs）具有其固有的大且易于功能化的表面积和孔体积，特别适合于高效输送多种治疗剂。当与其他有机/无机纳米材料结合时，所得的有机/无机 - MSN杂化物表现出独特的协同作用和更大的多功能性。在本文中，我们描述了MSNs以及有机/无机 - MSN杂化物在联合治疗与诊断——诊疗——生物医学应用方面的现状和未来前景。
