Liu Miaoxing, Fang Fang, Song Xiangwei, Yu Fen, Li Fengshun, Shi Xiaotong, Xue Chaowen, Chen Tingtao, Wang Xiaolei
College of Chemistry, NanChang University, NanChang, Jiangxi 330088, China.
J Mater Chem B. 2016 Apr 21;4(15):2544-2547. doi: 10.1039/c6tb00576d. Epub 2016 Apr 5.
The first visible three-mode switchable antibiotic nanocomposite, including "Packaged" (low toxicity and high stability), "On" (potent antibacterial activity, including drug-resistant strains) and "Off" (easy separation) modes, was synthesized to address several problems caused by antibiotic abuses. Some potential applications were discussed by using animal experiments and 3D printing separately.
首个可见的三模式可切换抗生素纳米复合材料被合成出来，以解决抗生素滥用所引发的若干问题。该复合材料具有“封装”（低毒性和高稳定性）、“开启”（强效抗菌活性，包括耐药菌株）和“关闭”（易于分离）三种模式。分别通过动物实验和3D打印探讨了其一些潜在应用。
