Liu Yiwei, Cao Xiaoqin, Kong Rongmei, Du Gu, Asiri Abdullah M, Lu Qun, Sun Xuping
Department of Chemistry and Chemical Engineering, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, Sichuan, China.
J Mater Chem B. 2017 Mar 14;5(10):1901-1904. doi: 10.1039/c6tb02882a. Epub 2017 Feb 24.
It is of significant importance for the design of electrodes to construct enhanced electrochemical sensing platforms, and a nanoarray offers an ideal architecture for the detection of molecules. In this communication, we demonstrate that cobalt phosphide nanowire array grown in situ on titanium mesh (CoP NA/TM) exhibits high catalytic activity towards electrooxidation of glucose. As a non-enzymatic electrochemical glucose sensor, this CoP NA/TM catalytic electrode possesses superior analytical performance with a short response time of less than 5 s, a wide linear range of 0.0005-1.5 mM, a low detection limit of 0.1 μM (S/N = 3), a high sensitivity of 5168.6 μA mM cm, and a remarkable selectivity and long-term stability for glucose detection. We further demonstrate the successful use of such glucose biosensors in human blood serum and fruit juice.
构建增强型电化学传感平台对于电极设计至关重要，而纳米阵列可为分子检测提供理想架构。在本通讯中，我们证明原位生长在钛网上的磷化钴纳米线阵列（CoP NA/TM）对葡萄糖的电氧化具有高催化活性。作为一种非酶电化学葡萄糖传感器，这种CoP NA/TM催化电极具有优异的分析性能，响应时间短于5秒，线性范围宽达0.0005 - 1.5 mM，检测限低至0.1 μM（S/N = 3），灵敏度高达5168.6 μA mM cm，且对葡萄糖检测具有出色的选择性和长期稳定性。我们进一步证明了此类葡萄糖生物传感器在人血清和果汁中的成功应用。
