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培养细胞衍生的脱细胞基质:迈向未来十年的综述

Cultured cell-derived decellularized matrices: a review towards the next decade.

作者信息

Hoshiba T

机构信息

Frontier Center for Organic Materials, Yamagata University, 4-3-16 Jonan, Yonezawa, Yamagata 992-8510, Japan.

出版信息

J Mater Chem B. 2017 Jun 21;5(23):4322-4331. doi: 10.1039/c7tb00074j. Epub 2017 Mar 24.

DOI:10.1039/c7tb00074j
PMID:32263962
Abstract

In the past decade, many cell-derived decellularized matrices have been prepared for various purposes. Cell-derived decellularized matrices have many advantages for inducing specific cell functions although there are still many problems that need to be solved. This review summarizes the points that need to be considered for the preparation of cell-derived decellularized matrices and provides examples of these matrices inducing cellular functions. Moreover, the problems that need to be solved in the next decade for the further application of cell-derived decellularized matrix technology have been summarized.

摘要

在过去十年中,人们制备了许多用于各种目的的细胞衍生脱细胞基质。细胞衍生脱细胞基质在诱导特定细胞功能方面具有许多优势,尽管仍有许多问题需要解决。本文综述了制备细胞衍生脱细胞基质时需要考虑的要点,并提供了这些基质诱导细胞功能的实例。此外,还总结了未来十年细胞衍生脱细胞基质技术进一步应用需要解决的问题。

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