King Alice A K, Matta-Domjan Brigitta, Large Matthew J, Matta Csaba, Ogilvie Sean P, Bardi Niki, Byrne Hugh J, Zakhidov Anvar, Jurewicz Izabela, Velliou Eirini, Lewis Rebecca, La Ragione Roberto, Dalton Alan B
Materials Physics, University of Sussex, Brighton, UK.
J Mater Chem B. 2017 Nov 7;5(41):8178-8182. doi: 10.1039/c7tb02065a. Epub 2017 Oct 16.
The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes; as two dimensional sheets and on three dimensional textiles. Raman spectroscopy is used to confirm the presence of chondroitin sulfate, which is critical in light of the unreliability of traditional dye based assays for carbon nanomaterial substrates. The textile exhibits a very high affinity for chondrocyte growth and could present a route to implantable, flexible cartilage scaffolds with tuneable mechanical properties.
在排列的碳纳米管支架上，二维薄片和三维织物上均证实了软骨细胞的有效生长和软骨的形成。拉曼光谱用于确认硫酸软骨素的存在，鉴于基于传统染料的碳纳米材料底物检测方法不可靠，这一点至关重要。这种织物对软骨细胞生长表现出非常高的亲和力，可能为具有可调节机械性能的可植入、柔性软骨支架提供一条途径。
