中央外侧丘脑核刺激通过调节全身麻醉期间跨区域、分层特异性活动来唤醒皮层。
Central Lateral Thalamic Nucleus Stimulation Awakens Cortex via Modulation of Cross-Regional, Laminar-Specific Activity during General Anesthesia.
机构信息
Feil Family Brain and Mind Research Institute, Weill Cornell Medical College, New York, NY 10065, USA.
出版信息
Neuron. 2020 Apr 8;106(1):1-3. doi: 10.1016/j.neuron.2020.02.016.
PMID:32272061
Abstract
Experiments identify cortical layer specific effects during induced arousal from general anesthesia. In this issue of Neuron, Redinbaugh et al. (2020) find evidence that central lateral thalamic nucleus electrical stimulation reactivates the cortex by restoring deep-layer firing rates and modulating feedforward and feedback connectivity.
摘要
实验确定了在全麻诱导唤醒过程中皮质层的特定作用。在本期《神经元》杂志上，Redinbaugh 等人（2020）发现，通过恢复深层放电率并调节前馈和反馈连接，中央外侧丘脑核电刺激可使大脑皮层重新活跃，这为该发现提供了证据。
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