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柠檬酸和次氯酸钠作为消毒剂对牛支原体的杀灭效果。

Efficacy of citric acid and sodium hypochlorite as disinfectants against Mycoplasma bovis.

机构信息

Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, University of Melbourne, Victoria, 3010, Australia.

Ministry for Primary Industries, Mycoplasma bovis Directorate, Biosecurity New Zealand, Wellington, 6140, New Zealand; Kate Sawford Epidemiological Consulting Pty Ltd., New South Wales, 2622, Australia.

出版信息

Vet Microbiol. 2020 Apr;243:108630. doi: 10.1016/j.vetmic.2020.108630. Epub 2020 Feb 26.

Abstract

Mycoplasma bovis, a cattle pathogen of major economic importance across the globe, causes a range of diseases, including pneumonia and mastitis. Because of the limited options for effective treatment of these diseases, prevention and control are preferred to diagnosis and treatment. In this study, the efficacies of citric acid and sodium hypochlorite as disinfectants against M. bovis were tested using a modification of a standardised method for assessing the efficacy of disinfectants against bacteria. A citric acid concentration of 0.5 % was found to be an effective disinfectant, reducing infectivity by close to 10 fold, while sodium hypochlorite at 1% was found to have similar efficacy to 0.5 % citric acid. A 0.04 % concentration of sodium hypochlorite was effective against M. bovis only in the absence of any organic material. Under these conditions, 0.25 % citric acid found to have similar efficacy. These findings indicate that 0.5 % citric acid or 1 % sodium hypochlorite are likely to be effective disinfectants for M. bovis under field conditions and 0.04 % sodium hypochlorite or 0.25 % citric acid are likely to be effective following removal of organic material.

摘要

牛支原体是一种具有全球重要经济意义的牛病原体,可引起多种疾病,包括肺炎和乳腺炎。由于对这些疾病进行有效治疗的选择有限,因此预防和控制优于诊断和治疗。在这项研究中,使用标准化方法评估消毒剂对细菌的功效的改良方法,测试了柠檬酸和次氯酸钠作为消毒剂对 M. bovis 的功效。发现柠檬酸浓度为 0.5%是一种有效的消毒剂,可将感染力降低近 10 倍,而 1%的次氯酸钠的功效与 0.5%柠檬酸相似。0.04%的次氯酸钠在没有任何有机物质的情况下才对 M. bovis 有效。在这些条件下,发现 0.25%柠檬酸具有相似的功效。这些发现表明,在田间条件下,0.5%柠檬酸或 1%次氯酸钠可能是 M. bovis 的有效消毒剂,而在去除有机物质后,0.04%次氯酸钠或 0.25%柠檬酸可能是有效的。

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