Arola H
Dept. of Public Health, University of Tampere, Finland.
Scand J Gastroenterol. 1988 Sep;23(7):851-5. doi: 10.3109/00365528809090772.
Detection of urinary galactose with a special test strip has been shown to work well with the lactose tolerance test with ethanol. In this study the strips were used in combination with a lactose load alone or with another alcohol, beta-pyridylcarbinol, and the results were compared with those of the urinary lactose tolerance test with ethanol (ULTTE) as the reference method. Sixty-nine patients were studied. With lactose alone the specificity was 83%, the sensitivity 88%, and the kappa coefficient 0.61. It is concluded that the strip test for hypolactasia works without ethanol with sufficient reliability for the daily clinical work of a general practitioner. Adding beta-pyridylcarbinol to the test does not markedly increase the validity of the test.
用一种特殊试纸条检测尿半乳糖已被证明在乙醇乳糖耐量试验中效果良好。在本研究中,这些试纸条单独与乳糖负荷或与另一种醇类β - 吡啶甲醇联合使用,并将结果与以乙醇进行的尿乳糖耐量试验(ULTTE)作为参考方法的结果进行比较。对69例患者进行了研究。单独使用乳糖时,特异性为83%,敏感性为88%,kappa系数为0.61。得出的结论是,用于检测乳糖酶缺乏的试纸条试验在不使用乙醇的情况下也能有效进行,对于全科医生的日常临床工作具有足够的可靠性。在试验中添加β - 吡啶甲醇并不会显著提高试验的有效性。