Massrey Chrissie, Abdulkader Marwah M, Hattab Eyas, Iwanaga Joe, Loukas Marios, Tubbs R Shane
Department of Anatomical Sciences, St. George's University, St. George's, Grenada, West Indies.
Department of Pathology, King Fahad Specialist Hospital, Dammam, Saudi Arabia.
Anat Cell Biol. 2020 Mar;53(1):15-20. doi: 10.5115/acb.19.051. Epub 2020 Feb 19.
The sympathetic trunk ganglia contain the cell bodies of neurons. However, some patients who undergo sympathectomy can develop compensatory hyperhidrosis. To evaluate for ectopic pathways, the present anatomical study was performed. Ten adult cadavers underwent dissection of the spinal canal and removal of randomly selected ventral roots, which were submitted for histological analysis. Random ventral root samples were taken from cervical, thoracic, and lumbosacral regions in each specimen. Each histological section was then analyzed and the presence or absence of sympathetic cells documented for level and position within the ventral root. Of all samples, a sympathetic nerve cell was found in 80% of ventral roots. At least one sympathetic cell was found in these 80%. Most sympathetic cells were found in the proximal one-third of the ventral root. Such cells were found at all spinal levels and no specific level within a vertebral region was found to house a greater concentration of these cells. No statistical significance was found when comparing sides or sex. Our study confirmed that sympathetic cells exist in the majority of human ventral roots. Such data might better explain various clinical presentations and postoperative complications/findings.
交感干神经节包含神经元的细胞体。然而，一些接受交感神经切除术的患者可能会出现代偿性多汗症。为了评估异位通路，进行了本解剖学研究。对10具成年尸体进行椎管解剖，并随机选取腹侧神经根进行切除，将其送去做组织学分析。在每个标本中，从颈、胸和腰骶部区域随机采集腹侧神经根样本。然后对每个组织学切片进行分析，并记录腹侧神经根内交感细胞的存在与否及其水平和位置。在所有样本中，80%的腹侧神经根中发现了交感神经细胞。在这80%的样本中至少发现了一个交感细胞。大多数交感细胞位于腹侧神经根的近端三分之一处。在所有脊髓节段均发现了此类细胞，且未发现椎体区域内有特定节段含有更高浓度的这些细胞。比较两侧或性别时未发现统计学意义。我们的研究证实，大多数人类腹侧神经根中存在交感细胞。这些数据可能更好地解释各种临床表现以及术后并发症/发现。
