Brumsted J R, Mead P B, Gibson M
Department of Obstetrics and Gynecology, College of Medicine, University of Vermont, Burlington 05405.
Sex Transm Dis. 1988 Jul-Sep;15(3):144-7. doi: 10.1097/00007435-198807000-00005.
The concentration of the protein CA-125 in serum was determined in women with a normal pelvis visualized at laparoscopy (control group, n = 15) and compared with serum levels of this protein in women with pelvic inflammatory disease (PID) (n = 14). Mean serum concentrations of CA-125 were similar in the two groups: 17.4 +/- 2.3 (SE) units/ml for the control group vs. 17.0 +/- 4.3 units/ml for those with PID (P greater than 0.05). In addition, women with chlamydial cervicitis, histologically confirmed endometritis, and laparoscopically documented salpingitis had CA-125 levels that were not significantly different from those of controls. We conclude that serum levels of CA-125 will not be useful in the diagnosis of PID.
对腹腔镜检查显示盆腔正常的女性（对照组，n = 15）测定血清中蛋白质CA - 125的浓度，并与盆腔炎（PID）女性（n = 14）的该蛋白质血清水平进行比较。两组的CA - 125平均血清浓度相似：对照组为17.4±2.3（SE）单位/毫升，PID患者为17.0±4.3单位/毫升（P>0.05）。此外，经组织学证实有衣原体宫颈炎、子宫内膜炎以及腹腔镜记录有输卵管炎的女性，其CA - 125水平与对照组无显著差异。我们得出结论，CA - 125血清水平对PID的诊断无帮助。
