Jacobs School of Medicine and Biomedical Sciences, University at Buffalo.
Virginia Tech Carilion Research Institute.
Behav Med. 2021 Jul-Sep;47(3):194-204. doi: 10.1080/08964289.2020.1712581. Epub 2020 Apr 10.
The majority of people with prediabetes transition to type 2 diabetes. Research has suggested that persons with type 2 diabetes are likely to discount the future and focus on immediate rewards. This study was designed to assess whether this process of delay discounting (DD) is associated with glycemic regulation, medication adherence and eating and exercise behaviors in adults with prediabetes. Participants included 81 adults with prediabetes who were also prescribed hypertension or dyslipidemia drugs, which is common for people with prediabetes. Participants completed adjusting amount DD $100 and $1000 tasks, as well assessments of glycemic control (Hemoglobin (Hb) A1c), medication adherence, diet quality, and objectively measured physical activity. Relationships between DD and these variables were assessed. Results showed higher rates of DD were related to higher HbA1c; as well as poorer medication adherence, lower diet quality and lower physical activity. Hierarchical regression showed that the association between minority status, a known risk factor for type 2 diabetes, was moderated by DD, as minorities with higher DD had greater HbA1c values. Delay discounting may represent a novel target to prevent progression from prediabetes to type 2 diabetes.
大多数糖尿病前期患者会发展为 2 型糖尿病。有研究表明，2 型糖尿病患者可能会低估未来而专注于即时回报。本研究旨在评估在患有糖尿病前期的成年人中，这种延迟折扣（DD）过程是否与血糖调节、药物依从性以及饮食和运动行为有关。参与者包括 81 名被诊断患有糖尿病前期且同时被开高血压或血脂异常药物的成年人，这在糖尿病前期患者中很常见。参与者完成了调整 100 美元和 1000 美元 DD 金额的任务，以及血糖控制（血红蛋白（Hb）A1c）、药物依从性、饮食质量和客观测量的身体活动评估。评估了 DD 与这些变量之间的关系。结果表明，较高的 DD 率与较高的 HbA1c 有关；同时还与较差的药物依从性、较低的饮食质量和较低的身体活动有关。分层回归显示，少数族裔身份（2 型糖尿病的已知风险因素）与 DD 之间的关联受到调节，因为 DD 较高的少数族裔 HbA1c 值更高。延迟折扣可能代表预防从糖尿病前期进展为 2 型糖尿病的新目标。
