Mohile Nimish A, Blakeley Jaishri O, Gatson Na Tosha N, Hottinger Andreas F, Lassman Andrew B, Ney Douglas E, Olar Adriana, Schiff David, Shih Helen A, Strowd Roy, van den Bent Martin J, Ziu Mateo
Department of Neurology, University of Rochester Medical Center.
Department of Neurology, Johns Hopkins University.
Neuro Oncol. 2020 Apr 11;22(7):912-7. doi: 10.1093/neuonc/noaa090.
The COVID-19 outbreak is posing unprecedented risks and challenges for all communities and healthcare systems, worldwide. There are unique considerations for many adult patients with gliomas who are vulnerable to the novel coronavirus due to older age and immunosuppression. As patients with terminal illnesses, they present ethical challenges for centers that may need to ration access to ventilator care due to insufficient critical care capacity. It is urgent for the neuro-oncology community to develop a pro-active and coordinated approach to the care of adults with gliomas in order to provide them with the best possible oncologic care while also reducing their risk of viral infection during times of potential healthcare system failure. In this article, we present an approach developed by an international multi-disciplinary group to optimize the care of adults with gliomas during this pandemic. We recommend measures to promote strict social distancing and minimize exposures for patients, address risk and benefit of all therapeutic interventions, pro-actively develop end of life plans, educate patients and caregivers and ensure the health of the multi-disciplinary neuro-oncology workforce. This pandemic is already changing neuro-oncologic care delivery around the globe. It is important to highlight opportunities to maximize the benefit and minimize the risk of glioma management during this pandemic and potentially, in the future.
新型冠状病毒肺炎疫情正在给全球所有社区和医疗系统带来前所未有的风险与挑战。许多成年神经胶质瘤患者因年龄较大和免疫抑制而容易感染新型冠状病毒,对此需要特别加以考虑。作为晚期疾病患者,由于重症监护能力不足,他们给那些可能需要对呼吸机护理进行配给的医疗中心带来了伦理挑战。神经肿瘤学界迫切需要制定一种积极主动且协调一致的方法来护理成年神经胶质瘤患者,以便在为他们提供尽可能最佳的肿瘤治疗的同时,在潜在的医疗系统失灵期间降低其病毒感染风险。在本文中,我们介绍了一个国际多学科小组所制定的一种方法,以在此次大流行期间优化成年神经胶质瘤患者的护理。我们建议采取措施,促进严格的社交距离并尽量减少患者的接触机会,评估所有治疗干预措施的风险和益处,积极制定临终计划,对患者和护理人员进行教育,并确保多学科神经肿瘤医护人员的健康。此次大流行已经在改变全球神经肿瘤护理的提供方式。重要的是要强调在此次大流行期间以及未来可能的情况下,将神经胶质瘤管理的益处最大化并将风险最小化的机会。