食物成瘾与 2 型糖尿病患者代谢控制、医疗并发症和抑郁的关联。
Associations of food addiction with metabolic control, medical complications and depression among patients with type 2 diabetes.
机构信息
Endocrinology and Nutrition Department, Hospital Son Llàtzer, University Institute of Health Science Research (IUNICS) and Health Research Institute of Balearic Islands (IdISBA), Ctra Manacor km 4, 07198, Palma de Mallorca, Baleares, Spain.
Hormonal Laboratory, Hospital Son Llàtzer, Ctra Manacor km 4, 07198, Palma de Mallorca, Baleares, Spain.
出版信息
Acta Diabetol. 2020 Sep;57(9):1093-1100. doi: 10.1007/s00592-020-01519-3. Epub 2020 Apr 10.
AIMS
Food addiction (FA) is conceptualized as a behavioral pattern that is similar in some ways to addictions to alcohol and other substances. This disorder has not been well studied among patients with type 2 diabetes (T2DM). We aimed to analyze if there is any relationship between FA and clinical or psychological variables among patients with T2DM.
METHODS
Three hundred patients with T2DM were analyzed cross-sectionally. Participants were evaluated for the presence of FA by completing the Yale Food Addiction Scale 2.0 questionnaire.
RESULTS
29.3% of patients screened positive for FA. Patients with FA had a greater BMI (33.41 ± 7.5 vs. 31.6 ± 5.9 kg/m; p = 0.04). HbA1c was higher among individuals with FA (7.9 ± 4.4 vs. 7.6 ± 1.4%, p = 0.008). The proportion of subjects with diabetic retinopathy, neuropathy and nephropathy was greater among patients with criteria for FA compared with patients without this condition (25% vs. 13.2%, 29.5% vs. 21.8% and 32% vs. 22.3%; p = 0.03, p = 0.05 and p = 0.05, respectively). The percentage of patients with FA with significant depressive symptoms was also greater (36.4% vs. 18.5%; p = 0.002).
CONCLUSIONS
The presence of FA among T2DM patients implied a worse glycaemic control. Microvascular complications and depressive symptoms were higher among these patients.
目的
食物成瘾（FA）被概念化为一种行为模式，在某些方面与酒精和其他物质成瘾相似。这种疾病在 2 型糖尿病（T2DM）患者中尚未得到很好的研究。我们旨在分析 T2DM 患者中 FA 与临床或心理变量之间是否存在任何关系。
方法
对 300 名 T2DM 患者进行横断面分析。通过完成耶鲁食物成瘾量表 2.0 问卷评估参与者 FA 的存在。
结果
29.3%的患者筛查出 FA 阳性。有 FA 的患者 BMI 更高（33.41±7.5 与 31.6±5.9 kg/m2；p=0.04）。FA 患者的 HbA1c 更高（7.9±4.4 与 7.6±1.4%，p=0.008）。与没有 FA 条件的患者相比，有 FA 条件的患者糖尿病视网膜病变、神经病变和肾病的比例更高（25%与 13.2%，29.5%与 21.8%和 32%与 22.3%；p=0.03、p=0.05 和 p=0.05）。有 FA 的患者有明显抑郁症状的比例也更高（36.4%与 18.5%；p=0.002）。
结论
T2DM 患者存在 FA 意味着血糖控制更差。这些患者的微血管并发症和抑郁症状更高。
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