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来自药用真菌白囊耙齿菌HFG1102培养物中的艾里烷型和颤木烷型倍半萜。

Irlactane and Tremulane Sesquiterpenes from the Cultures of the Medicinal Fungus Irpex lacteus HFG1102.

作者信息

Chen He-Ping, Ji Xu, Li Zheng-Hui, Feng Tao, Liu Ji-Kai

机构信息

School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, 430074, People's Republic of China.

School of Chemical Science and Technology, Yunnan University, Kunming, 650091, People's Republic of China.

出版信息

Nat Prod Bioprospect. 2020 Apr;10(2):89-100. doi: 10.1007/s13659-020-00239-z. Epub 2020 Apr 10.

DOI:10.1007/s13659-020-00239-z
PMID:32277439
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7176803/
Abstract

A new irlactane-type, namely irlactin K (1), and 22 tremulane-type sesquiterpenes including fourteen previously undescribed ones, namely irpexolactins A-N (2-15), and a known irlactane-type sesquiterpenoid, were isolated from the fermentation broth of the medicinal fungus Irpex lacteus HFG1102. The structures of all the isolates were characterized by extensive spectroscopic methods, including 1D and 2D NMR and MS spectroscopic analysis. The absolute configurations of irlactin K and the known compound conocenol B (20) were established by single-crystal X-ray diffraction analysis. The vasorelaxant effects of irlactin K (1), irpexolactins A (2), C (4), K (12), and irlactam (22) were evaluated.

摘要

从药用真菌桦褐孔菌HFG1102的发酵液中分离出一种新的irlactane型化合物，即irlactin K（1），以及22种倍半萜类化合物，其中包括14种以前未描述过的化合物，即irpexolactins A - N（2 - 15），还有一种已知的irlactane型倍半萜类化合物。所有分离物的结构均通过广泛的光谱方法进行表征，包括一维和二维核磁共振光谱以及质谱分析。irlactin K和已知化合物conocenol B（20）的绝对构型通过单晶X射线衍射分析确定。评估了irlactin K（1）、irpexolactins A（2）、C（4）、K（12）和irlactam（22）的血管舒张作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30d6/7176803/99148ecd7929/13659_2020_239_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30d6/7176803/43997a2ec6cc/13659_2020_239_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30d6/7176803/f78135a7ca0e/13659_2020_239_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30d6/7176803/9ff3835f0a40/13659_2020_239_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30d6/7176803/ee3a1bf84101/13659_2020_239_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30d6/7176803/99148ecd7929/13659_2020_239_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30d6/7176803/43997a2ec6cc/13659_2020_239_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30d6/7176803/f78135a7ca0e/13659_2020_239_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30d6/7176803/9ff3835f0a40/13659_2020_239_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30d6/7176803/ee3a1bf84101/13659_2020_239_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30d6/7176803/99148ecd7929/13659_2020_239_Fig5_HTML.jpg

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3
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