Pratap-Chand R, Sinniah M, Salem F A
Department of Medicine, University Hospital, Kubang Kerian, Kelantan, Malaysia.
Acta Neurol Scand. 1988 Sep;78(3):185-9. doi: 10.1111/j.1600-0404.1988.tb03643.x.
Cognitive impairment has been reported to occur in minor head injury (concussion). The value of the P300 evoked potential as a measure of cerebral concussion was studied in 20 patients with minor head injury and compared with the data from 20 normal subjects. Significant abnormalities of the P300 latency and amplitude were noted in these patients in the post-concussion period. The abnormalities improved completely on repeat testing. The correlation of the P300 to other parameters of head injury is discussed. The P300 constitutes a simple laboratory test that is sensitive measure of cerebral dysfunction in concussive head injuries.
据报道，认知障碍会发生在轻度头部损伤（脑震荡）中。对20例轻度头部损伤患者研究了P300诱发电位作为脑震荡测量指标的价值，并与20名正常受试者的数据进行了比较。在这些患者的脑震荡后时期，观察到P300潜伏期和波幅有显著异常。重复测试时，这些异常完全改善。讨论了P300与头部损伤其他参数的相关性。P300构成了一项简单的实验室检测，是脑震荡性头部损伤中脑功能障碍的敏感测量指标。
