National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Chinese Center for Tropical Diseases Research, Shanghai 200025,China; School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai 200025,China; Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai 200025, China; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai 200025, China; WHO Collaborating Centre for Tropical Diseases, Shanghai 200025, China.
Binyang Center for Disease Control and Prevention, Binyang 530400, China.
Acta Trop. 2020 Jul;207:105436. doi: 10.1016/j.actatropica.2020.105436. Epub 2020 Apr 10.
Clonorchiasis is caused by the ingestion of raw freshwater fish containing Clonorchis sinensis larvae. Health education is crucial in sustainable control of clonorchiasis but extremely challenging when dealing with adults. To investigate if education in children would be a beneficial long-term approach, a cluster-controlled trial was implemented in two primary schools between 2017 and 2019 in Binyang county, Guangxi, China. A baseline survey was conducted in both schools, and then comprehensive education activities were implemented in the interventional one. Six and 12 months later, all pupils were subjected to a survey to assess the potential change of knowledge, practice and belief related to clonorchiasis. Finally, 247 pupils in interventional school and 151 ones in control were eligible for analysis. In the interventional school, the percentage of pupils with knowledge on transmission route, early symptoms, complications and carcinogenicity increased from 15.0% to 78.5% (p < 0.001), from 6.5% to 36.8% (p < 0.001), from 4.0% to 93.9% (p < 0.001) and from 4.5% to 49.4% (p < 0.001) after 12 months. In this school, 16 pupils (6.5%) had eaten raw freshwater fish during the year immediately before the baseline survey, a number that decreased to 3 (1.2%) (p = 0.002) 12 months later. The percentage of students had the belief on the ability not to eat raw freshwater fish in the future was 70.9% at the baseline and 97.2% 12 months later (p < 0.001). Although knowledge related to clonorchiasis also increased in the control school, the absolute percentage of changes was lower; in particular, practice and belief had not changed.
华支睾吸虫病是由摄入含有华支睾吸虫幼虫的生淡水鱼引起的。健康教育对于可持续控制华支睾吸虫病至关重要，但在面对成年人时却极具挑战性。为了探讨对儿童进行教育是否是一种有益的长期方法，我们于 2017 年至 2019 年在中国广西宾阳县的两所小学开展了一项整群对照试验。在两所学校均进行了基线调查，然后对干预组的学校开展了全面的教育活动。6 个月和 12 个月后，所有学生都接受了一项调查，以评估与华支睾吸虫病相关的知识、实践和信念的潜在变化。最终，共有 247 名干预学校的学生和 151 名对照学校的学生符合分析条件。在干预学校，关于传播途径、早期症状、并发症和致癌性的知识知晓率从 15.0%上升到 78.5%（p<0.001），从 6.5%上升到 36.8%（p<0.001），从 4.0%上升到 93.9%（p<0.001），从 4.5%上升到 49.4%（p<0.001）。在该学校，16 名学生（6.5%）在基线调查前一年食用过生淡水鱼，而 12 个月后，这一数字减少到 3 名（1.2%）（p=0.002）。在基线时有 70.9%的学生认为自己将来没有能力不吃生淡水鱼，而 12 个月后这一比例上升到 97.2%（p<0.001）。尽管对照学校的华支睾吸虫病相关知识也有所增加，但变化的绝对百分比较低；特别是实践和信念没有改变。
