School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Acupuncture Clinical Research Center, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Chin J Integr Med. 2021 Dec;27(12):940-946. doi: 10.1007/s11655-020-3195-3. Epub 2020 Apr 1.
To evaluate the quality of the existing studies and summarize evidence of important outcomes of meta-analyses/systematic reviews (MAs/SRs) of CFS.
Potentially eligible studies were searched in the following electronic databases from inception to 1 September, 2019: Chinese Biomedical Literature Database (CBM), China Science and Technology Journal Database (VIP), China National Knowledge Infrastructure (CNKI), WanFang Database (WF), Web of Science, Embase, PubMed and Cochrane Library. Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) was used to evaluate the quality of evidence. The methodological quality of the literature was evaluated by A Measure Tool to Assess Systematic Reviews-2 (AMSTAR-2) and the quality of the report was assessed by Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA). The intra-class correlation coefficient was used to assess the consistency of the reviewers, with an overall intraclass correlation coefficient score of 0.967.
Ten MAs/SRs were included. The overall conclusions were that acupuncture had good safety and efficacy in the treatment of CFS, but some of these results were contradictory. The GRADE indicated that out of the 17 outcomes, high-quality evidence was provided in 0 (0%), moderate in 3 (17.65%), low in 10 (58.82%), and very low in 4 (23.53%). The results of AMSTAR-2 showed that the methodological quality of all included studies was critically low. The PRISMA statement revealed that 8 articles (80%) were in line with 20 of the 27-item checklist, and 2 articles (20%) matched with 10-19 of the 27 items.
We found that acupuncture on treating CFS has the advantage for efficacy and safety, but the quality of SRs/MAs of acupuncture for CFS need to be improved.
评价现有研究的质量，并总结慢性疲劳综合征（CFS）荟萃分析/系统评价（MAs/SRs）重要结局的证据。
从建库至 2019 年 9 月 1 日，检索以下电子数据库以获取潜在的合格研究：中国生物医学文献数据库（CBM）、中国科技期刊数据库（VIP）、中国知网（CNKI）、万方数据库（WF）、Web of Science、Embase、PubMed 和 Cochrane 图书馆。使用推荐、评估、开发和评估分级（GRADE）评估证据质量。使用 AMSTAR-2 评估文献的方法学质量，使用 PRISMA 评估报告质量。使用组内相关系数评估审稿人的一致性，总体组内相关系数评分为 0.967。
纳入了 10 项 MAs/SRs。总体结论是，针灸治疗 CFS 具有良好的安全性和疗效，但其中一些结果存在矛盾。GRADE 表明，在 17 项结果中，0 项（0%）提供了高质量证据，3 项（17.65%）为中等质量，10 项（58.82%）为低质量，4 项（23.53%）为极低质量。AMSTAR-2 的结果表明，所有纳入研究的方法学质量均极低。PRISMA 声明显示，8 篇文章（80%）符合 27 项清单中的 20 项，2 篇文章（20%）符合 10-19 项。
我们发现针灸治疗 CFS 在疗效和安全性方面具有优势，但针灸治疗 CFS 的 SRs/MAs 的质量需要提高。
