Andra Cristea, Suwalska Anna, Dumitrescu Ana Maria, Kerob Delphine, Delva Catherine, Hasse-Cieślińska Marta, Solymosi Agnes, Arenbergerova Monika
Private Practice, Bucharest, Romania.
Primaderm, Warszawa, Poland.
Clin Cosmet Investig Dermatol. 2020 Mar 30;13:253-257. doi: 10.2147/CCID.S240437. eCollection 2020.
Facial blemishes resulting from skin disorders have a significant effect on the patient's self-esteem and impact quality of life (QOL).
To assess the impact of a corrective cosmetic (CC) on QOL on top of skin quality parameters.
An international observational study was conducted on subjects with visible facial flaws that would benefit from a corrective cosmetic. Investigators collected data regarding demographics, QOL using the Skindex-16 scale, skin dryness and tautness, subject and investigator satisfaction, cosmetic acceptability and tolerance at baseline and after 4 to 6 weeks of daily use.
A total of 1840 subjects participated; the mean age was 31.5±11.1 and 95% were women. Acne accounted for 48.9% of skin conditions, followed by melasma (16.7%) and rosacea (15.3%). Of the subjects 81.2% had at least 10% of the face affected and the condition was rated as disfiguring by 45.3% of the subjects; 45.0% and 44.4%, respectively, had neither taut nor dry skin at baseline. Baseline Skindex-16 scores for symptoms, emotions, functioning and overall were 1.4±1.3, 3.5±1.6, 2.4±1.8 and 2.4±1.3, respectively, on a scale from 0 to 6. Compliance was 96.0±10.6%. At the end of the study, Skindex-16 scores had significantly (p<0.0001) improved for all parameters, as did skin dryness and tautness. Subject and investigator satisfaction were high or very high; cosmetic acceptability was high or very high and local tolerance good or very good.
The tested corrective cosmetic significantly improved the QOL of subjects with significant facial flaws, skin tautness and dryness, and was well tolerated.
皮肤疾病导致的面部瑕疵对患者的自尊有重大影响，并影响生活质量（QOL）。
评估矫正性化妆品（CC）在皮肤质量参数之外对生活质量的影响。
对有明显面部瑕疵且能从矫正性化妆品中获益的受试者进行了一项国际观察性研究。研究人员收集了有关人口统计学、使用Skindex-16量表的生活质量、皮肤干燥和紧绷度、受试者及研究者满意度、化妆品可接受性和耐受性的数据，数据收集时间为基线时以及每日使用4至6周后。
共有1840名受试者参与；平均年龄为31.5±11.1岁，95%为女性。痤疮占皮肤疾病的48.9%，其次是黄褐斑（16.7%）和酒渣鼻（15.3%）。81.2%的受试者面部至少10%受到影响，45.3%的受试者将病情评为毁容；基线时分别有45.0%和44.4%的受试者皮肤既不紧绷也不干燥。症状、情绪、功能和总体的基线Skindex-16评分分别为1.4±1.3、3.5±1.6、2.4±1.8和2.4±1.3，评分范围为0至6。依从性为96.0±10.6%。研究结束时，所有参数的Skindex-16评分均显著改善（p<0.0001），皮肤干燥和紧绷度也有所改善。受试者和研究者的满意度高或非常高；化妆品可接受性高或非常高，局部耐受性良好或非常良好。
所测试的矫正性化妆品显著改善了有明显面部瑕疵、皮肤紧绷和干燥的受试者的生活质量，且耐受性良好。
