Sandbank M, Abramovici A, Wolf R, Ben David E
Department of Dermatology, Beilinson Medical Center, Tel Aviv University, Sackler School of Medicine, Israel.
Am J Dermatopathol. 1988 Oct;10(5):415-8.
Topical application of citral on male rat skin induces hyperplasia of the sebaceous glands. Ultrastructural study showed that this hyperplasia is manifested by an increase in number of the partially differentiated cells of the gland. Citral was found in fat droplets of the mature differentiated and partially differentiated cells. Because citral causes an increase in testosterone level, we conclude that the sebaceous gland hyperplasia is related to androgen activity.
在雄性大鼠皮肤上局部涂抹柠檬醛会导致皮脂腺增生。超微结构研究表明,这种增生表现为腺体部分分化细胞数量增加。在成熟分化和部分分化细胞的脂肪滴中发现了柠檬醛。由于柠檬醛会导致睾酮水平升高,我们得出结论,皮脂腺增生与雄激素活性有关。