Institute of Health and Society, University of Oslo, P.O. Box 1089, N-0318, Oslo, Blindern, Norway.
Department of Neurohabilitation, Oslo University Hospital, P.O. Box 4956, N-0424, Oslo, Nydalen, Norway.
BMC Musculoskelet Disord. 2020 Apr 13;21(1):235. doi: 10.1186/s12891-020-03246-w.
Physical activity is associated with positive health effects, but individuals with neuromuscular disease (NMD) may experience constraints being physically active. There is a gap in the literature on the activity level of people with NMDs, and therefore we did a study to determine the physical activity level in people with Limb-Girdle muscular dystrophy (LGMD) and Charcot-Marie-Tooth disease (CMT).
This study used a cross-sectional design to obtain self-reported physical activity and sitting time among individuals with LGMD and CMT who were recruited from the Norwegian registry for hereditary and congenital neuromuscular diseases.
A total of 127 respondents who filled out questionnaires about either physical activity or sitting time were included in the analysis. Seventy (55.1%) had a diagnosis of CMT and 57 (44.9%) had a diagnosis of LGMD. Seventy-three (57.5%) respondents were female and 54 (42.5%) were male. Among the 108 respondents with available physical activity data, 44.4% reported being physically inactive. Among the 109 respondents with available sitting time data, the average sitting time was 8.6 h. Longer sitting time was associated with higher physical inactivity.
Among people with LGMD and CMT in our study, 55.6% reported being physically active. Respondents with LGMD and CMT reported longer sitting time and less physical activity compared with healthy respondents in other studies. Further research should explore variables and measures that can promote physical activity among people with neuromuscular conditions.
身体活动与积极的健康影响有关，但患有神经肌肉疾病（NMD）的个体可能在身体活动方面受到限制。关于 NMD 患者活动水平的文献存在空白，因此我们进行了一项研究，以确定肢带型肌营养不良症（LGMD）和 Charcot-Marie-Tooth 病（CMT）患者的身体活动水平。
本研究采用横断面设计，从挪威遗传性和先天性神经肌肉疾病登记处招募 LGMD 和 CMT 患者，获取他们的自我报告身体活动和久坐时间数据。
共有 127 名填写了身体活动或久坐时间问卷的受访者被纳入分析。其中 70 人（55.1%）诊断为 CMT，57 人（44.9%）诊断为 LGMD。73 名（57.5%）受访者为女性，54 名（42.5%）为男性。在 108 名有可用身体活动数据的受访者中，44.4%报告身体不活跃。在 109 名有可用久坐时间数据的受访者中，平均久坐时间为 8.6 小时。久坐时间越长，身体活动不活跃的比例越高。
在我们的研究中，LGMD 和 CMT 患者中有 55.6%报告身体活跃。与其他研究中健康受访者相比，LGMD 和 CMT 患者报告的久坐时间更长，身体活动更少。进一步的研究应探索可促进神经肌肉疾病患者身体活动的变量和措施。
