Caballería J, Torres M, Camps J, Parés A, Reixach M, Rodés J
Liver Unit, Hospital Clinic i Provincial, University of Barcelona, Spain.
Alcohol Alcohol. 1988;23(5):403-7. doi: 10.1093/oxfordjournals.alcalc.a044835.
The usefulness of a urine-alcohol determination in the evaluation of abstinence in alcoholic liver disease has been investigated in 181 patients. Alcohol was tested in morning urine samples collected on a follow-up visit in 103 patients, and the results were compared with those in 78 patients, where three samples were collected within the same week; one in the morning and two in the evening. Although the percentage of urine samples containing alcohol measured in a morning sample was similar to the patients' self-report (31% and 34%, respectively), urine analysis identified an additional 7% of patients who denied alcohol intake. Alternatively, serial urine-alcohol determinations were significantly more effective than patient reports (54% and 35.9%, respectively, P less than 0.01), particularly when urine was collected in the evenings. This difference was due mainly to the reluctance of women to admit drinking (7.4% of positive self reports vs 51% of women with alcohol positive urine samples, P less than 0.001). We conclude that serial measurements of alcohol in urine were useful tests which should be used to complement personal interview in the control of abstinence in patients with alcoholic liver disease.
我们对181例酒精性肝病患者进行了尿酒精检测在评估戒酒情况中的效用研究。对103例患者随访时采集的晨尿样本进行酒精检测，并将结果与78例患者的结果进行比较，这78例患者在同一周内采集了三个样本，一个晨尿样本和两个晚尿样本。虽然晨尿样本中检测到含酒精的尿液样本百分比与患者自我报告相似（分别为31%和34%），但尿液分析发现另外7%否认饮酒的患者尿液中含酒精。另外，连续尿酒精检测比患者报告显著更有效（分别为54%和35.9%，P<0.01），尤其是在采集晚尿样本时。这种差异主要是由于女性不愿承认饮酒（自我报告阳性的女性占7.4%，而尿酒精检测阳性的女性占51%，P<0.001）。我们得出结论，连续检测尿酒精是有用的检测方法，应用于补充对酒精性肝病患者戒酒情况的个人访谈。
