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教育案例：具有非典型特征的毛细胞型星形细胞瘤

Educational Case: Pilocytic Astrocytoma With Atypical Features.

作者信息

Tjota Melissa Y, Pytel Peter

机构信息

Department of Pathology, University of Chicago, IL, USA.

出版信息

Acad Pathol. 2020 Mar 30;7:2374289520912498. doi: 10.1177/2374289520912498. eCollection 2020 Jan-Dec.

DOI:10.1177/2374289520912498
PMID:32284965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7119228/
Abstract

http://journals.sagepub.com/doi/10.1177/2374289517715040..

摘要

http://journals.sagepub.com/doi/10.1177/2374289517715040.. （此为网址，无需翻译具体内容）

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76a6/7119228/fa37e94bfb53/10.1177_2374289520912498-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76a6/7119228/a2d106a6f3a7/10.1177_2374289520912498-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76a6/7119228/8cb435c2762d/10.1177_2374289520912498-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76a6/7119228/ac875f1d83a1/10.1177_2374289520912498-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76a6/7119228/fa37e94bfb53/10.1177_2374289520912498-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76a6/7119228/a2d106a6f3a7/10.1177_2374289520912498-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76a6/7119228/8cb435c2762d/10.1177_2374289520912498-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76a6/7119228/ac875f1d83a1/10.1177_2374289520912498-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76a6/7119228/fa37e94bfb53/10.1177_2374289520912498-fig4.jpg

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本文引用的文献

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Integrating a Large Next-Generation Sequencing Panel into the Clinical Diagnosis of Gliomas Provides a Comprehensive Platform for Classification from FFPE Tissue or Smear Preparations.将大型下一代测序面板整合到胶质细胞瘤的临床诊断中，为从 FFPE 组织或涂片制备物进行分类提供了一个全面的平台。
J Neuropathol Exp Neurol. 2019 Mar 1;78(3):257-267. doi: 10.1093/jnen/nly130.
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Cancer statistics, 2019.癌症统计数据，2019 年。
CA Cancer J Clin. 2019 Jan;69(1):7-34. doi: 10.3322/caac.21551. Epub 2019 Jan 8.
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Pathology Competencies for Medical Education and Educational Cases.
医学教育病理学能力与教育案例
Acad Pathol. 2017 Jul 24;4:2374289517715040. doi: 10.1177/2374289517715040. eCollection 2017 Jan-Dec.
4
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.2016 年世界卫生组织中枢神经系统肿瘤分类：概述。
Acta Neuropathol. 2016 Jun;131(6):803-20. doi: 10.1007/s00401-016-1545-1. Epub 2016 May 9.
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Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma.放疗联合丙卡巴肼、洛莫司汀和长春新碱治疗低级别胶质瘤
N Engl J Med. 2016 Apr 7;374(14):1344-55. doi: 10.1056/NEJMoa1500925.
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Pilocytic astrocytoma: pathology, molecular mechanisms and markers.毛细胞型星形细胞瘤：病理学、分子机制及标志物
Acta Neuropathol. 2015 Jun;129(6):775-88. doi: 10.1007/s00401-015-1410-7. Epub 2015 Mar 20.
7
The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas.端粒延长的替代性表型与高级别儿童和成人星形细胞瘤中 ATRX 表达缺失显著相关：214 例星形细胞瘤的多机构研究。
Mod Pathol. 2013 Nov;26(11):1425-32. doi: 10.1038/modpathol.2013.90. Epub 2013 Jun 14.
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BRAF-KIAA1549 fusion predicts better clinical outcome in pediatric low-grade astrocytoma.BRAF-KIAA1549 融合预示着儿科低级别星形细胞瘤有更好的临床结局。
Clin Cancer Res. 2011 Jul 15;17(14):4790-8. doi: 10.1158/1078-0432.CCR-11-0034. Epub 2011 May 24.
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IDH1 and IDH2 mutations in gliomas.胶质瘤中的异柠檬酸脱氢酶1（IDH1）和异柠檬酸脱氢酶2（IDH2）突变
N Engl J Med. 2009 Feb 19;360(8):765-73. doi: 10.1056/NEJMoa0808710.
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Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas.串联重复产生一种新的致癌性BRAF融合基因，这在大多数毛细胞型星形细胞瘤中都有体现。
Cancer Res. 2008 Nov 1;68(21):8673-7. doi: 10.1158/0008-5472.CAN-08-2097.