Department of Surgery, The University of Auckland, Auckland, New Zealand.
Mechanical and Automotive Engineering, School of Engineering, RMIT University, Bundoora, Victoria, Australia.
Rhinology. 2020 Aug 1;58(4):349-359. doi: 10.4193/Rhin20.011.
The aim of this study was to investigate using computational fluid dynamics (CFD) the effects on nasal aerodynamics of two different techniques for reducing the inferior turbinate. This may assist in surgical planning to select the optimal procedure.
Virtual surgery using two techniques of turbinate reduction was performed in eight nasal airway obstruction patients. Three bilateral nasal airway models for each patient were compared: 1) Pre-operative 2) Bilateral inferior turbinoplasty 3) Bilateral total inferior turbinate resection (ITR). Two representative healthy models were included. CFD modeling of airflow was performed under steady-state, laminar, inspiratory conditions.
Nasal airway resistance was slightly more reduced following ITR compared to turbinoplasty due to loss of the pressure gradient at the head of the IT. Turbinoplasty resulted in ventilation, pressure and wall shear stress profiles closer to those of healthy models. A more prominent jet-like course of the main flow stream was observed inferiorly in the ITR group.
Nasal air conditioning was significantly altered following IT surgery. Overall differences between the groups were small and are unlikely to bear influence on nasal function in normal environments. Further studies using a larger number of patients and healthy subjects are required, attempting to establish a clinical correlation with long-term outcomes such as the perception of nasal patency, mucosal crusting and drying, and air conditioning in different environments. Since a large proportion of IT mucosa remains following turbinoplasty, future dependence on topical therapy should also be considered.
本研究旨在通过计算流体动力学(CFD)研究两种不同鼻甲缩小技术对鼻腔空气动力学的影响。这可能有助于手术规划以选择最佳手术方案。
对 8 例鼻腔气道阻塞患者进行了两种鼻甲缩小技术的虚拟手术。对每位患者的三个双侧鼻腔气道模型进行了比较:1)术前;2)双侧下鼻甲成形术;3)双侧下鼻甲全切除术(ITR)。还包括了两个具有代表性的健康模型。在稳态、层流、吸气条件下对气流进行了 CFD 建模。
由于 IT 头部的压力梯度丧失,ITR 后鼻腔气道阻力略有降低。与健康模型相比,下鼻甲成形术导致通气、压力和壁面剪切应力分布更接近健康模型。在 ITR 组中,观察到主要气流流向下部更突出的射流状。
IT 手术后鼻腔空气调节发生了显著变化。各组之间的总体差异较小,不太可能对正常环境下的鼻腔功能产生影响。需要进一步使用更多患者和健康受试者进行研究,尝试与长期结果(如对鼻腔通畅的感知、粘膜结壳和干燥以及不同环境下的空气调节)建立临床相关性。由于下鼻甲成形术后仍保留了大量的 IT 粘膜,因此还应考虑未来对局部治疗的依赖。