Bundesanstalt für Materialforschung und - prüfung (BAM), Richard-Willstätter-Str. 11, D-12489 Berlin, Germany.
Analyst. 2020 May 21;145(10):3490-3494. doi: 10.1039/d0an00319k. Epub 2020 Apr 14.
The employment of type-I pyrethroids for airplane disinfection in recent years underlines the necessity to develop sensing schemes for the rapid detection of these pesticides directly at the point-of-use. Antibody-gated indicator-releasing materials were thus developed and implemented with test strips for lateral-flow assay-based analysis employing a smartphone for readout. Besides a proper matching of pore sizes and gating macromolecules, the functionalization of both the material's outer surface as well as the strips with PEG chains enhanced system performance. This simple assay allowed for the detection of permethrin as a target molecule at concentrations down to the lower ppb level in less than 5 minutes.
近年来，I 型拟除虫菊酯在飞机消毒中的应用强调了开发快速检测这些农药的传感方案的必要性，直接在使用点进行检测。因此，开发了抗体门控指示剂释放材料，并将其与测试条一起用于基于侧流分析的分析，使用智能手机进行读取。除了适当匹配孔径和门控大分子外，还通过 PEG 链对材料的外表面和测试条进行功能化，从而提高了系统性能。这种简单的检测方法允许在不到 5 分钟的时间内检测到拟除虫菊酯作为目标分子，浓度低至较低的 ppb 水平。
