Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Medical Rehabilitation Clinic, Clinical Centre of Vojvodina, Novi Sad, Serbia.
Pain Pract. 2020 Sep;20(7):724-736. doi: 10.1111/papr.12900. Epub 2020 May 19.
The goal of the present study was to explore additional evidence of validity of the Serbian version of the Central Sensitization Inventory (CSI), a patient-reported outcome measure of symptoms that have been found to be associated with central sensitization (CS). The CSI has been found to be psychometrically sound, and has demonstrated evidence of convergent and discriminant validity in numerous published studies and in multiple languages.
CSI data were collected from 399 patients with chronic pain who had various diagnoses and from 146 pain-free controls. In addition, the patient sample completed a battery of validated patient-reported outcome measures of sleep problems, cognitive problems, pain catastrophizing, pain-related fear-avoidance, decreased quality of life, and decreased perception of social support. Six patient subgroups were formed, with presumably different levels of CS (including those with fibromyalgia, multiple pain sites, and localized pain sites).
Significant differences were found in total CSI scores among the controls and patient subgroups. Those with fibromyalgia and multiple pathologies scored highest and the control subjects scored lowest. Other patient-reported CS-related symptom dimensions were significantly correlated with total CSI scores. When the patients were divided into CSI severity subgroups (from subclinical to extreme), the severity of these other symptom dimensions increased with the severity of CSI scores.
The current study successfully demonstrated additional evidence of the convergent and discriminant validity of the Serbian version of the CSI.
本研究旨在探索塞族版中枢敏感化量表（CSI）的更多有效性证据，该量表是一种患者报告的与中枢敏感化（CS）相关症状的结果测量方法。CSI 在许多已发表的研究和多种语言中已被证明具有良好的心理测量学特性，并具有收敛和判别效度的证据。
从有各种诊断的 399 名慢性疼痛患者和 146 名无痛对照者中收集 CSI 数据。此外，患者样本完成了一套经过验证的患者报告的睡眠问题、认知问题、疼痛灾难化、疼痛相关的恐惧回避、生活质量下降和社会支持感知下降的结果测量。形成了六个具有不同 CS 水平（包括纤维肌痛、多部位疼痛和局部疼痛部位）的患者亚组。
在对照组和患者亚组之间，CSI 总分存在显著差异。纤维肌痛和多病理患者得分最高，对照组得分最低。其他与 CS 相关的患者报告症状维度与 CSI 总分显著相关。当患者被分为 CSI 严重程度亚组（从亚临床到极端）时，这些其他症状维度的严重程度随着 CSI 评分的严重程度而增加。
本研究成功地证明了塞族版 CSI 的收敛和判别效度的更多证据。
