Pain Clinic, Department of Anaesthesiology, University Medical Center, Georg August University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany.
Physiological Psychology, Otto-Friedrich- University of Bamberg, Bamberg, Germany.
BMC Musculoskelet Disord. 2021 Aug 18;22(1):708. doi: 10.1186/s12891-021-04481-5.
The Central Sensitization Inventory (CSI) is a screening tool designed to detect symptoms related to Central Sensitization (CS) and Central Sensitivity Syndromes (CSS) by measuring the degree of related phenomena. The objective of this study was to create a German, culturally-adapted version of the CSI and to test its psychometric properties.
A German version of the CSI (CSI-GE) was developed, culturally-adapted, and pretested for comprehensibility. The psychometric properties of the resulting version were validated in a clinical study with chronic pain and pain-free control subjects. To assess retest reliability, the CSI-GE was administered twice to a subgroup of patients. Structural validity was tested using factor analyses. To investigate construct validity a hypotheses testing approach was used, including (1) correlations between the CSI-GE and several other well-established questionnaires as well as (2) an investigation of the CSI-GE discriminative power between different subgroups of participants believed to have different degrees of CS.
The CSI-GE showed excellent reliability, including high test-retest characteristics. Factor analyses confirmed a bi-factor dimensionality as has been determined previously. Analysing construct validity 6 out of 11 hypotheses (55%) were met. CSI-GE scores differentiated between subgroups according to expectations. Correlations between CSI-GE scores and other questionnaires suggested that none of the correlated constructs was identical, but there was overlap with other questionnaires based on symptom load. Several correlations did not fit with our current understanding of CS.
The CSI-GE appears to be a reliable tool for measuring CS/CSS-related symptomatology. Whether this implies that the CSI-GE measures the degree of CS within an individual subject remains unknown. The resulting score should be interpreted cautiously until further clarification of the construct.
中央敏化量表（CSI）是一种筛查工具，旨在通过测量相关现象的程度来检测与中央敏化（CS）和中央敏感性综合征（CSS）相关的症状。本研究的目的是创建一个德国文化适应的 CSI 版本，并测试其心理测量特性。
开发了 CSI 的德文版本（CSI-GE），进行了文化适应，并进行了预测试以确保理解性。通过对慢性疼痛和无痛对照受试者进行临床研究来验证该版本的心理测量特性。为了评估重测信度，将 CSI-GE 分两次施用于患者亚组。使用因子分析测试结构有效性。为了研究构念效度，采用假设检验方法，包括（1）CSI-GE 与其他几个成熟问卷之间的相关性，以及（2）CSI-GE 在被认为具有不同程度 CS 的不同参与者亚组之间的区分能力的调查。
CSI-GE 显示出极好的可靠性，包括高重测特征。因子分析证实了先前确定的双因素维度性。分析构念效度时，满足了 11 个假设中的 6 个（55%）。CSI-GE 分数根据预期区分不同亚组。CSI-GE 分数与其他问卷之间的相关性表明，没有一个相关构念是相同的，但基于症状负荷与其他问卷存在重叠。一些相关性与我们目前对 CS 的理解不符。
CSI-GE 似乎是测量 CS/CSS 相关症状的可靠工具。这是否意味着 CSI-GE 测量个体患者的 CS 程度仍不清楚。在进一步阐明构念之前，应谨慎解释由此产生的分数。
