From the Department of Anesthesia, The Hospital for Sick Children, Toronto, Ontario, Canada.
Department of Anesthesiology, Perioperative and Pain Medicine, Children's Hospital of Boston, Harvard School of Medicine, Boston, Massachusetts.
Anesth Analg. 2020 Jul;131(1):61-73. doi: 10.1213/ANE.0000000000004872.
The severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019 [COVID-19]) pandemic has challenged medical systems and clinicians globally to unforeseen levels. Rapid spread of COVID-19 has forced clinicians to care for patients with a highly contagious disease without evidence-based guidelines. Using a virtual modified nominal group technique, the Pediatric Difficult Intubation Collaborative (PeDI-C), which currently includes 35 hospitals from 6 countries, generated consensus guidelines on airway management in pediatric anesthesia based on expert opinion and early data about the disease. PeDI-C identified overarching goals during care, including minimizing aerosolized respiratory secretions, minimizing the number of clinicians in contact with a patient, and recognizing that undiagnosed asymptomatic patients may shed the virus and infect health care workers. Recommendations include administering anxiolytic medications, intravenous anesthetic inductions, tracheal intubation using video laryngoscopes and cuffed tracheal tubes, use of in-line suction catheters, and modifying workflow to recover patients from anesthesia in the operating room. Importantly, PeDI-C recommends that anesthesiologists consider using appropriate personal protective equipment when performing aerosol-generating medical procedures in asymptomatic children, in addition to known or suspected children with COVID-19. Airway procedures should be done in negative pressure rooms when available. Adequate time should be allowed for operating room cleaning and air filtration between surgical cases. Research using rigorous study designs is urgently needed to inform safe practices during the COVID-19 pandemic. Until further information is available, PeDI-C advises that clinicians consider these guidelines to enhance the safety of health care workers during airway management when performing aerosol-generating medical procedures. These guidelines have been endorsed by the Society for Pediatric Anesthesia and the Canadian Pediatric Anesthesia Society.
严重急性呼吸综合征冠状病毒 2(冠状病毒病 2019 [COVID-19])大流行使医疗系统和全球临床医生面临前所未有的挑战。COVID-19 的迅速传播迫使临床医生在没有基于证据的指南的情况下照顾患有高度传染性疾病的患者。使用虚拟改良名义群体技术,目前包括来自 6 个国家的 35 家医院的儿科困难插管协作组(PeDI-C)根据专家意见和有关该疾病的早期数据就小儿麻醉中的气道管理生成了共识指南。PeDI-C 在护理过程中确定了总体目标,包括最大限度地减少雾化呼吸分泌物、最大限度地减少与患者接触的临床医生人数,并认识到未确诊的无症状患者可能会排出病毒并感染医护人员。建议包括给予镇静药物、静脉麻醉诱导、使用视频喉镜和带套囊的气管插管、使用在线吸引导管以及修改工作流程以便在手术室从麻醉中恢复患者。重要的是,PeDI-C 建议麻醉师在为无症状儿童或已知或疑似 COVID-19 儿童进行产生气溶胶的医疗程序时考虑使用适当的个人防护设备。在有条件的情况下,气道程序应在负压室中进行。在进行手术病例之间应留出足够的时间进行手术室清洁和空气过滤。迫切需要使用严格的研究设计进行研究,以为 COVID-19 大流行期间的安全实践提供信息。在获得更多信息之前,PeDI-C 建议临床医生考虑这些指南,以在进行产生气溶胶的医疗程序时增强气道管理过程中医护人员的安全性。这些指南得到了儿科麻醉学会和加拿大儿科麻醉学会的认可。