Fedorko Daniel P
Microbiology Service, Warren Grant Magnuson Clinical Center, National Institutes of Health, Building 10, Room 2C385, Bethesda, MD 20892-1508, USA.
Clin Microbiol Newsl. 2002 May 15;24(10):76-79. doi: 10.1016/S0196-4399(02)80020-4. Epub 2002 Jul 25.
Recent reports of two nosocomial outbreaks of -associated disease caused by toxin A-deficient strains emphasize that these strains can cause disease. Laboratories using an assay that detects only toxin A as their primary diagnostic test risk misdiagnosis of cases or outbreaks in the institutions they serve. Repeat testing can account for a significant portion of a laboratory's testing workload. Published data are available to support laboratory rules for rejection of repeat stool specimens within 7 days of an initial specimen. There are also substantial published data to support laboratory rejection of formed stools sent to the laboratory for testing.
近期有关于两起由毒素A缺陷菌株引起的医院感染暴发的报告,强调这些菌株可引发疾病。仅采用检测毒素A的检测方法作为主要诊断测试的实验室,存在误诊其所服务机构中病例或暴发情况的风险。重复检测可能占实验室检测工作量的很大一部分。已有公开数据支持实验室制定在初次标本采集后7天内拒收重复粪便标本的规则。也有大量公开数据支持实验室拒收送至实验室用于检测的成形粪便。