Haselhorst U, Schenk H, Beyer I, Uebelhack R, Franke E, Kielstein V
Institute of Pathological Biochemistry, Academy of Medicine Magdeburg, GDR.
Clin Physiol Biochem. 1988;6(5):281-4.
The pattern of gangliosides in membranes of erythrocytes was examined in healthy donors, in acute schizophrenics without neuroleptic treatment and in alcohol-dependent patients. 7 different gangliosides could be detected. Healthy donors were characterized by the following ganglioside pattern: GX = 5.8%; GT1b = 6.7%; FucGD1b = 5.2%; GD1a = 12.6%, GD3 = 9.2%, SPG = 43.5%, and GM3 = 17.0%. In schizophrenic patients the GM3 and GD3 fractions were increased. No difference was found between the control group and the alcoholics.
对健康献血者、未接受抗精神病药物治疗的急性精神分裂症患者以及酒精依赖患者的红细胞膜神经节苷脂模式进行了检测。可检测到7种不同的神经节苷脂。健康献血者的神经节苷脂模式特征如下：GX = 5.8%；GT1b = 6.7%；FucGD1b = 5.2%；GD1a = 12.6%，GD3 = 9.2%，SPG = 43.5%，GM3 = 17.0%。精神分裂症患者的GM3和GD3组分增加。对照组和酗酒者之间未发现差异。
