Kozykeyeva Raushan A, Datkhayev Ubaidilla M, Srivedavyasasri Radhakrishnan, Ajayi Temitayo O, Patsayev Anapiya K, Kozykeyeva Raikhan A, Ross Samir A
Department of Organization and Management and Economics of Pharmacy and Clinical Pharmacy, School of Pharmacy, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.
Center for Natural Product Research, School of Pharmacy, University of Mississippi, Oxford, MS 38677, USA.
ScientificWorldJournal. 2020 Mar 30;2020:7821310. doi: 10.1155/2020/7821310. eCollection 2020.
is a perennial plant with deep green color and covered with soft hairs and has a slightly aromatic odor. This genus has been used in traditional medicines of China, Greece, and European countries. It was mainly used as a haemostatic, a tonic for asthenia, and an astringent for diarrhea. Agrimony is part of the division Magnoliophyta; class is represented by order Rosales, family Rosaceae, of the genus . Family Rosaceae-or pink eels-is one of the largest families of flowering plants, including about 100 genera and 3000 species. Rosaceae is common in almost all areas of the globe where flowering plants can grow, but most of them are concentrated in the temperate and subtropical zones of the Northern Hemisphere. Phytochemical investigation on ethanolic extract of led to isolation of four flavonoid derivatives (kaempferol-3-glycoside, quercetin-3-O--arabinofuranosyl--D-galactopyranoside, 3-O-kaempherol 2,3-di-O-acetyl-4-O-(cis-p-coumaroyl)-6-O-(trans-p-coumaroyl)--D-glucosopyranoside, and catechin) alongside of sucrose. All the extracts, fractions, and isolated compounds were tested for antimicrobial and antiplasmodial activities. We also studied the chemical composition of essential oil obtained from the aerial part of . The essential oil constituents from the aerial part of were obtained using a steam-distillation method in wild growing conditions in Kazakhstan. The essential oil extracted from the aerial part of the plant was analyzed by gas chromatography-mass spectroscopy and its major components amounting to 100% were found to be -selinene (36.370%), -panasinsene (21.720%), hexadecanoic acid (7.839%), and 1,2-nonadiene (6.199%). Neither the extract nor the isolated compounds showed antimicrobial and antiplasmodial activities.
是一种多年生植物，颜色深绿，覆盖着柔软的绒毛，有轻微的芳香气味。该属植物已被用于中国、希腊和欧洲国家的传统药物中。它主要用作止血剂、虚弱滋补剂和腹泻收敛剂。龙牙草属于木兰植物门；纲由蔷薇目代表，蔷薇科，该属。蔷薇科——或蔷薇科植物——是开花植物中最大的科之一，包括约100个属和3000种。蔷薇科在几乎所有开花植物能够生长的全球区域都很常见，但大多数集中在北半球的温带和亚热带地区。对龙牙草乙醇提取物的植物化学研究导致分离出四种黄酮类衍生物（山奈酚-3-糖苷、槲皮素-3-O-α-阿拉伯呋喃糖基-β-D-吡喃半乳糖苷、3-O-山奈酚2,3-二-O-乙酰基-4-O-(顺式-p-香豆酰基)-6-O-(反式-p-香豆酰基)-β-D-葡萄糖吡喃糖苷和儿茶素）以及蔗糖。对所有提取物、馏分和分离出的化合物进行了抗菌和抗疟活性测试。我们还研究了从龙牙草地上部分获得的精油的化学成分。龙牙草地上部分的精油成分是在哈萨克斯坦野生生长条件下采用水蒸气蒸馏法获得的。通过气相色谱-质谱法分析从植物地上部分提取的精油，发现其占总量100%的主要成分是β-芹子烯(36.370%)、α-古芸烯(21.720%)、十六烷酸(7.839%)和1,2-壬二烯(6.199%)。提取物和分离出的化合物均未显示出抗菌和抗疟活性。
