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本文引用的文献

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Virtual screening and molecular simulation study of natural products database for lead identification of novel coronavirus main protease inhibitors.用于新型冠状病毒主要蛋白酶抑制剂先导物鉴定的天然产物数据库的虚拟筛选和分子模拟研究
J Biomol Struct Dyn. 2022 May;40(8):3655-3667. doi: 10.1080/07391102.2020.1848630. Epub 2020 Nov 19.
2
Evaluation of genetic toxicity, acute and sub-chronic oral toxicity and systemic safety of and 50% ethanolic extract mixture (APRG64) in vitro and in vivo (rodent and non-rodent animal models).评价[具体物质]与50%乙醇提取物混合物(APRG64)在体外和体内(啮齿动物和非啮齿动物模型)的遗传毒性、急性和亚慢性经口毒性以及全身安全性。
Toxicol Res. 2020 Apr 14;36(4):367-406. doi: 10.1007/s43188-020-00042-5. eCollection 2020 Oct.
3
Anti-viral activity of compounds from Agrimonia pilosa and Galla rhois extract mixture.杠板归和五倍子提取物混合物中化合物的抗病毒活性。
Bioorg Chem. 2019 Dec;93:103320. doi: 10.1016/j.bioorg.2019.103320. Epub 2019 Sep 26.
4
Neutralization of cholera toxin by Rosaceae family plant extracts.蔷薇科植物提取物对霍乱毒素的中和作用。
BMC Complement Altern Med. 2019 Jun 20;19(1):140. doi: 10.1186/s12906-019-2540-6.
5
Protective effects of p-coumaric acid against oxidant and hyperlipidemia-an in vitro and in vivo evaluation.对苯丙烯酸对氧化剂和高血脂的保护作用:体外和体内评价。
Biomed Pharmacother. 2019 Mar;111:579-587. doi: 10.1016/j.biopha.2018.12.074. Epub 2018 Dec 31.
6
Wallr. Extract Increases Stress Resistance and Prolongs Life Span in via Transcription Factor DAF-16 (FoxO Orthologue).沃尔提取物通过转录因子DAF-16(FoxO直系同源物)增强抗逆性并延长寿命。
Antioxidants (Basel). 2018 Dec 14;7(12):192. doi: 10.3390/antiox7120192.
7
The polyphenolic-polysaccharide complex of Agrimonia eupatoria L. as an indirect thrombin inhibitor - isolation and chemical characterization.龙牙草中多酚-多糖复合物作为间接凝血酶抑制剂的分离与化学特性。
Int J Biol Macromol. 2019 Mar 15;125:124-132. doi: 10.1016/j.ijbiomac.2018.12.017. Epub 2018 Dec 3.
8
Agrimonia procera exerts antimicrobial effects, modulates the expression of defensins and cytokines in colonocytes and increases the immune response in lipopolysaccharide-challenged piglets.高杆龙芽草具有抗菌作用,可调节结肠细胞中防御素和细胞因子的表达,并增强脂多糖刺激仔猪的免疫反应。
BMC Vet Res. 2018 Nov 15;14(1):346. doi: 10.1186/s12917-018-1680-0.
9
Antioxidant Properties of Ferulic Acid and Its Possible Application.阿魏酸的抗氧化特性及其可能的应用
Skin Pharmacol Physiol. 2018;31(6):332-336. doi: 10.1159/000491755. Epub 2018 Sep 20.
10
p-Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans.对羟基肉桂酸可改善秀丽隐杆线虫的氧化应激和渗透应激响应。
J Sci Food Agric. 2019 Feb;99(3):1190-1197. doi: 10.1002/jsfa.9288. Epub 2018 Sep 19.

仙鹤草的治疗效果

The therapeutic effects of Agrimonia eupatoria L.

机构信息

Department of Pharmacology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.

出版信息

Physiol Res. 2020 Dec 31;69(Suppl 4):S555-S571. doi: 10.33549/physiolres.934641.

DOI:10.33549/physiolres.934641
PMID:33646008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8603700/
Abstract

Agrimonia eupatoria L. is an herb of the Rosaceae family, widely used in traditional (folk) medicine for its beneficial effects. Its water extracts (infusions and decoctions) are used in the treatment of airway and urinary system diseases, digestive tract diseases, and chronic wounds. Phytochemical analyses of Agrimonia eupatoria L. identified a variety of bioactive compounds including tannins, flavonoids, phenolic acids, triterpenoids and volatile oils possessing antioxidant, immunomodulatory and antimicrobial activities. The authors review the available literature sources examining and discussing the therapeutic and pharmacological effects of Agrimonia eupatoria L. at the molecular level in vitro and in vivo.

摘要

龙牙草(Agrimonia eupatoria L.)是蔷薇科的一种草本植物,因其有益的作用而在传统(民间)医学中广泛使用。其水提取物(浸剂和煎剂)用于治疗呼吸道和泌尿系统疾病、消化道疾病和慢性伤口。对龙牙草(Agrimonia eupatoria L.)的植物化学分析鉴定了多种生物活性化合物,包括单宁、类黄酮、酚酸、三萜和挥发油,具有抗氧化、免疫调节和抗菌活性。作者回顾了现有的文献来源,检查和讨论了龙牙草(Agrimonia eupatoria L.)在体外和体内的分子水平上的治疗和药理学作用。