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视觉诱发电位在青光眼的早期诊断中的应用。文献综述。

Visual evoked potential in the early diagnosis of glaucoma. Literature review.

机构信息

Barnsley District Hospital, NHS Trust, Barnsley, South Yorkshire, Great Britain.

Ophthalmology Department, University Emergency Hospital Bucharest, Bucharest, Romania.

出版信息

Rom J Ophthalmol. 2020 Jan-Mar;64(1):15-20.

Abstract

Visual evoked potentials (VEP) are a significant visual electrophysiological diagnostic exam, which can be used as a suitable objective measure of optic nerve function. The topic was greatly debated and many correlations between the magnitude of the VEP latency parameters and parameters of Humphrey static perimetry suggested that the abnormal cortex responses in patients with glaucomatous changes could be tested by both electrophysiological and physical methods. Moreover, the optic nerve glaucomatous damage observed by reduction in ganglion cell layer and retinal fibre layer thickness through SD-OCT tests, which are known to precede Humphrey visual field defects, correlates with VEP latency parameters, thus consolidating the position of the VEP testing in glaucoma progression.

摘要

视觉诱发电位(VEP)是一种重要的视觉电生理诊断检查,可以作为视神经功能的客观测量指标。这个主题引发了广泛的讨论,许多研究表明 VEP 潜伏期参数的幅度与 Humphrey 静态视野计的参数之间存在相关性,这表明通过电生理和物理方法可以检测出青光眼患者皮质反应异常。此外,通过 SD-OCT 检查观察到的视神经青光眼损伤,即节细胞层和视网膜纤维层厚度减少,已知其先于 Humphrey 视野缺损,与 VEP 潜伏期参数相关,从而巩固了 VEP 测试在青光眼进展中的地位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbce/7141918/514026299717/RomJOphthalmol-64-15-g001.jpg

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