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视觉诱发电位在青光眼的早期诊断中的应用。文献综述。

Visual evoked potential in the early diagnosis of glaucoma. Literature review.

机构信息

Barnsley District Hospital, NHS Trust, Barnsley, South Yorkshire, Great Britain.

Ophthalmology Department, University Emergency Hospital Bucharest, Bucharest, Romania.

出版信息

Rom J Ophthalmol. 2020 Jan-Mar;64(1):15-20.

PMID:32292852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7141918/
Abstract

Visual evoked potentials (VEP) are a significant visual electrophysiological diagnostic exam, which can be used as a suitable objective measure of optic nerve function. The topic was greatly debated and many correlations between the magnitude of the VEP latency parameters and parameters of Humphrey static perimetry suggested that the abnormal cortex responses in patients with glaucomatous changes could be tested by both electrophysiological and physical methods. Moreover, the optic nerve glaucomatous damage observed by reduction in ganglion cell layer and retinal fibre layer thickness through SD-OCT tests, which are known to precede Humphrey visual field defects, correlates with VEP latency parameters, thus consolidating the position of the VEP testing in glaucoma progression.

摘要

视觉诱发电位(VEP)是一种重要的视觉电生理诊断检查,可以作为视神经功能的客观测量指标。这个主题引发了广泛的讨论,许多研究表明 VEP 潜伏期参数的幅度与 Humphrey 静态视野计的参数之间存在相关性,这表明通过电生理和物理方法可以检测出青光眼患者皮质反应异常。此外,通过 SD-OCT 检查观察到的视神经青光眼损伤,即节细胞层和视网膜纤维层厚度减少,已知其先于 Humphrey 视野缺损,与 VEP 潜伏期参数相关,从而巩固了 VEP 测试在青光眼进展中的地位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbce/7141918/be7bb6dcd768/RomJOphthalmol-64-15-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbce/7141918/514026299717/RomJOphthalmol-64-15-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbce/7141918/6e2053d9247d/RomJOphthalmol-64-15-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbce/7141918/be7bb6dcd768/RomJOphthalmol-64-15-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbce/7141918/514026299717/RomJOphthalmol-64-15-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbce/7141918/6e2053d9247d/RomJOphthalmol-64-15-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbce/7141918/be7bb6dcd768/RomJOphthalmol-64-15-g003.jpg

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ISCEV guide to visual electrodiagnostic procedures.国际临床视觉电生理学会视觉电诊断程序指南
Doc Ophthalmol. 2018 Feb;136(1):1-26. doi: 10.1007/s10633-017-9621-y. Epub 2018 Feb 3.
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Visual Evoked Potentials in Primary Open Angle Glaucoma.原发性开角型青光眼的视觉诱发电位
青光眼成像设备的诊断准确性:一项更新的荟萃分析。
Med J Islam Repub Iran. 2023 Apr 15;37:38. doi: 10.47176/mjiri.37.38. eCollection 2023.
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Insufficient Oligodendrocyte Turnover in Optic Nerve Contributes to Age-Related Axon Loss and Visual Deficits.视神经中少突胶质细胞的更替不足导致与年龄相关的轴突丢失和视觉缺陷。
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Prospective Assessment of Early Proton Therapy-Induced Optic Neuropathy in Patients With Intracranial, Orbital or Sinonasal Tumors: Impact of A Standardized Ophthalmological Follow Up.颅内、眼眶或鼻窦肿瘤患者早期质子治疗诱发视神经病变的前瞻性评估:标准化眼科随访的影响
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