Holopigian K, Snow J, Seiple W, Siegel I
Department of Ophthalmology, NYU Medical Center, NY 10016.
Doc Ophthalmol. 1988 Sep;70(1):103-15. doi: 10.1007/BF00154741.
Conflicting results have been obtained concerning the parametric properties of the pattern electroretinogram. These discrepancies may be due to the large amount of variability inherent in recording amplitudes. We have found the variability within a single stimulus condition to be so large (ranging from 30% to 67% of the mean value) that it could mask any underlying spatial frequency tuning. Changing the stimulus conditions failed to significantly reduce the observed variability, although changing recording conditions produced some reduction. The use of a narrower rejection band, a greater number of sweeps, and placement of the reference electrode on the ipsilateral ear (as opposed to the ipsilateral temple) combined to decrease variability of the pattern electroretinogram within a single recording session; however, intersession variability remained high. Therefore one must be careful in evaluating data from this technique, and caution is advised in its clinical use.
关于图形视网膜电图的参数特性，已得到相互矛盾的结果。这些差异可能是由于记录振幅中固有的大量变异性所致。我们发现，在单一刺激条件下的变异性非常大（范围为平均值的30%至67%），以至于可能掩盖任何潜在的空间频率调谐。改变刺激条件未能显著降低观察到的变异性，尽管改变记录条件产生了一定程度的降低。使用更窄的拒斥带、更多的扫描次数以及将参考电极放置在同侧耳上（而不是同侧颞部），共同作用可降低单次记录过程中图形视网膜电图的变异性；然而，不同记录时段之间的变异性仍然很高。因此，在评估该技术的数据时必须谨慎，并且在其临床应用中建议谨慎行事。
